D4010
2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate
≥96% (HPLC)
Sinônimo(s):
2′-deoxy-, 5′-triphosphate sodium salt, Guanosine, dGTP sodium salt hydrate
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About This Item
Fórmula empírica (Notação de Hill):
C10H16N5O13P3 · xNa+ · yH2O
Número CAS:
Peso molecular:
507.18 (anhydrous free acid basis)
Número MDL:
Código UNSPSC:
41106305
ID de substância PubChem:
NACRES:
NA.51
Preço e disponibilidade não estão disponíveis no momento.
Produtos recomendados
fonte biológica
synthetic (organic)
Ensaio
≥96% (HPLC)
Formulário
powder
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
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Aplicação
2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate has been used:
- as a component in a polymerase chain reaction (PCR) mixture for PCR product formation using AM-toxin primers[1]
- as an internal standard to improve the analytical performance of capillary electrophoresis (CE) analysis for the evaluation of the cleanup process[2]
- as a putative substrate in in vitro enzyme activity assay to incubate with nudix hydrolase 15 (NUDT15) protein for the evaluation of putative NUDT15 inhibitors[3]
Ações bioquímicas/fisiológicas
Deoxyguanosine 5′-triphosphate (dGTP), a purine deoxynucleotide, is a substrate of DNA polymerase(s) and reverse transcriptases. dGTP is useful to study the distribution, specificity, and kinetics of various nucleoside-triphosphatases (NTPase) and ribonucleotide reductases.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Genomic DNA is prone to oxidation by reactive oxygen species. A major product of DNA oxidation is the miscoding base 8-oxoguanine (8-oxoG). The mutagenic effects of 8-oxoG in mammalian cells are prevented by a DNA repair system consisting of 8-oxoguanine-DNA
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