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Documentos

17797

Sigma-Aldrich

Physcion

≥98.0% (TLC)

Sinônimo(s):

1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, 6-O-Methylemodin, 6-Methoxychrysophanic acid, Emodin-3-methyl ether, Parietin, Rheochrysidin

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About This Item

Fórmula empírica (Notação de Hill):
C16H12O5
Número CAS:
521-61-9
Peso molecular:
284.26
Beilstein:
6770499
Número CE:
208-315-7
Número MDL:
MFCD00017374
Código UNSPSC:
85151701
ID de substância PubChem:
57647675
NACRES:
NA.25

Ensaio

≥98.0% (TLC)

espectro de atividade do antibiótico

fungi

cadeia de caracteres SMILES

COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1

InChI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

chave InChI

FFWOKTFYGVYKIR-UHFFFAOYSA-N

Informações sobre genes

human ... ELA2(1991)

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Categorias relacionadas

Aplicação

Physcion can be used to study antibiotics, antifungals, bioactive small molecules and cell biology. Physcion has been used in a study to test the cytotoxicity of juglanthraquinone C on human cancer cells. Physcion has also been used in a study that investigated the metabolic regulatory effects of Rheum undulatum in a high-fat diet model.

Ações bioquímicas/fisiológicas

Anthraquinone-derivative found in medicinal herbs.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P264 - P270 - P301 + P312 - P501

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Aloe-emodin analytical standard

Supelco

93938

Aloe-emodin

Chrysophanol phyproof® Reference Substance

PHL89378

Chrysophanol

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside ≥98% (HPLC)

Sigma-Aldrich

SML0834

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside

Rhein technical grade

Sigma-Aldrich

275611

Rhein

Rhein phyproof® Reference Substance

PHL89385

Rhein

Polidatina ≥95% (HPLC)

Sigma-Aldrich

15721

Polidatina

Yao Yao et al.
Apoptosis : an international journal on programmed cell death, 17(8), 832-841 (2012-04-10)
Juglanthraquinone C (1,5-dihydroxy-9,10-anthraquinone-3-carboxylic acid, JC), a naturally occurring anthraquinone isolated from the stem bark of Juglans mandshurica, shows strong cytotoxicity in various human cancer cells in vitro. Here, we first performed a structure-activity relationship study of six anthraquinone compounds (JC
Phil-Dong Moon et al.
Molecules (Basel, Switzerland), 24(8) (2019-04-18)
Physcion is well known for the treatment of carcinoma. However, the therapeutic effect of physcion on atopic dermatitis (AD) through the inhibition of thymic stromal lymphopoietin (TSLP) level remains largely unknown. In this study, we investigated the anti-AD effect of
Simeon F Kouam et al.
Journal of natural products, 69(2), 229-233 (2006-02-28)
One new prenylated 1,4-anthraquinone and three new prenylated anthranols, named kengaquinone (1) and kenganthranols A (2), B (3), and C (4), were isolated from a hexane extract of the stem bark of Harungana madagascariensis. Six known compounds including anthraquinones, anthrones
Ming-Yi Shen et al.
PloS one, 6(11), e27480-e27480 (2011-11-17)
Plants provide a rich source of lead compounds for a variety of diseases. A novel approach combining phytochemistry and chemotaxis assays was developed and used to identify and study the mechanisms of action of the active compounds in F. japonica
Santosh Pandit et al.
Biofouling, 28(3), 279-287 (2012-03-23)
Polygonum cuspidatum is a plant with spreading rhizomes and numerous reddish-brown stems that has been used in Korean folk medicine to improve oral hygiene. Nevertheless, there are no reports related to its possible effect on the virulence of dental biofilms.
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