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R0600000

(−)-Riboflavina

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

Lactoflavina, Vitamina B2, Vitamina G

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About This Item

Fórmula empírica (Notação de Hill):
C17H20N4O6
Número CAS:
Peso molecular:
376.36
Beilstein:
97825
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

fonte biológica

fermentation/recombinant (Bacillus subtilis)

grau

pharmaceutical primary standard

Agency

EP

família API

riboflavin

forma

solid

fabricante/nome comercial

EDQM

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

pf

290 °C (dec.) (lit.)

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

chave InChI

AUNGANRZJHBGPY-SCRDCRAPSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Riboflavin is a type of vitamin B that plays a vital role in human nutrition and growth. It finds potential applications in biochemical redox reactions and is present in several foodstuffs, energy drinks, and vitamin formulations.

Aplicação

Riboflavin may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Simultaneous determination of niacinamide, pyridoxine, riboflavin, and thiamine in multivitamin products by high-pressure liquid chromatography
Walker MC, et al.
Journal of Pharmaceutical Sciences, 70(1), 99-101 (1981)
Simultaneous determination of nicotinamide, pyridoxine hydrochloride, thiamine mononitrate and riboflavin in multivitamin with minerals tablets by reversed-phase ion-pair high performance liquid chromatography
Li K
Biomedical Chromatography, 16(8), 504-507 (2002)
Differential pulse polarographic method development and validation of riboflavin in pharmaceutical formulation
Kashid LM and Patil SV
International Journal of Scientific Research, 5(2), 325-334 (2015)
Riboflavin
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 5(2), 3484-3485 (2008)
Simultaneous determination of riboflavin phosphate and other ingredients in a multivitamin pharmaceutical preparation by on-line automated LC coupled with pre-column immobilized enzyme reactor
Ono M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(1-2), 325-334 (2002)

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