PHR1051

Propylene glycol

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): 1,2-Propanediol, Propylene glycol
• Fórmula linear: CH₃CH(OH)CH₂OH
• Número CAS: 57-55-6
• Peso molecular: 76.09
• Beilstein: 1340498
• Número CE: 200-338-0
• Número MDL: MFCD00064272
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823081
• Número E: E1520
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to USP 1576708
• densidade de vapor: 2.62 (vs air)
• pressão de vapor: 0.08 mmHg ( 20 °C)
• família API: propylene glycol
• Certificado de análise (CofA): current certificate can be downloaded
• temperatura de autoignição: 779 °F
• Lim. expl.: 12.5 %
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• índice de refração: n20/D 1.432 (lit.)
• p.e.: 187 °C (lit.)
• pf: −60 °C (lit.)
• densidade: 1.036 g/mL at 25 °C (lit.)
• aplicação(ões): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care; pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: CC(O)CO
• InChI: 1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
• chave InChI: DNIAPMSPPWPWGF-UHFFFAOYSA-N

Descrição

Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propylene glycol is commonly utilized as a penetration enhancer in topical dermatological formulations, either alone or in combined form with other penetration enhancing agents, like fatty acids.[1]

Aplicação

Propylene glycol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.[2][3][1]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB9658 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 219.2 °F - closed cup
• Ponto de fulgor (°C): 104 °C - closed cup