Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

M3761

Supelco

Metronidazole

analytical standard

Sinônimo(s):

2-Methyl-5-nitroimidazole-1-ethanol

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Fórmula empírica (Notação de Hill):
C6H9N3O3
Número CAS:
Peso molecular:
171.15
Beilstein:
611683
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

forma

crystalline

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

159-161 °C (lit.)

espectro de atividade do antibiótico

Gram-negative bacteria
parasites

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)

formato

neat

Modo de ação

DNA synthesis | interferes

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC1=NC=C([N+]([O-])=O)N1CCO

InChI

1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3

chave InChI

VAOCPAMSLUNLGC-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Metronidazole is a nitroimidazole drug, used particularly against infections caused by anaerobic bacteria and protozoa in humans and domestic animals.

Aplicação

The analytical standard can be used as follows:
  • Cyclic voltametric determination of metronidazole at carbon paste electrode (CPE) in three different brands of metronidazole tablets
  • Simultaneous determination of metronidazole, diloxanide, spiramycin, and cliquinol in pharmaceutical dosage forms by reversed-phase high-performance liquid chromatography coupled to photodiode array detector (RP-HPLC-DAD)
  • Development of an electrochemical sensor based on polydopamine/carboxylic multi-walled carbon nano-tubes (MWCNTs-COOH) nanocomposites for the determination of metronidazole
  • Liquid chromatography–ion trap mass spectrometry (LC-MS/MS based analysis of metronidazole in water, sediment, and fish tissue samples
  • Determination of metronidazole using an electrochemical sensor based on multi-walled carbon nanotubes (MWCNTs) and chitosan-nickel complexes (CTS-Ni) in tablets, human urine, and serum samples

Outras notas

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Carc. 1B - Muta. 1B - STOT RE 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


Choose from one of the most recent versions:

Certificados de análise (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 3

1 of 3

Ampicilina

Sigma-Aldrich

A9518

Ampicilina

Tinidazole VETRANAL®, analytical standard

Supelco

32553

Tinidazole

Alison L Huckenpahler et al.
Translational vision science & technology, 9(10), 18-18 (2020-09-29)
To observe and characterize cone degeneration and regeneration in a selective metronidazole-mediated ablation model of ultraviolet-sensitive (UV) cones in zebrafish using in vivo optical coherence tomography (OCT) imaging. Twenty-six sws1:nfsB-mCherry;sws2:eGFP zebrafish were imaged with OCT, treated with metronidazole to selectively
Sonja Löfmark et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 50 Suppl 1, S16-S23 (2010-01-14)
Metronidazole has been used for the treatment of infections for >45 years and is still successfully used for the treatment of trichomoniasis, amoebiasis, and giardiasis. Anaerobic bacterial infections caused by Bacteroides species, fusobacteria, and clostridia respond favorably to metronidazole therapy.
Manoj K Puthia et al.
Eukaryotic cell, 7(3), 435-443 (2007-12-25)
Blastocystis is a ubiquitous enteric protozoan found in the intestinal tracts of humans and a wide range of animals. Evidence accumulated over the last decade suggests association of Blastocystis with gastrointestinal disorders involving diarrhea, abdominal pain, constipation, nausea, and fatigue.
Claire Chevalier et al.
Cell metabolism, 32(4), 575-590 (2020-09-12)
Osteoporosis is the most prevalent metabolic bone disease, characterized by low bone mass and microarchitectural deterioration. Here, we show that warmth exposure (34°C) protects against ovariectomy-induced bone loss by increasing trabecular bone volume, connectivity density, and thickness, leading to improved
Samrah Masud et al.
Autophagy, 15(5), 796-812 (2019-01-25)
Innate immune defense against intracellular pathogens, like Salmonella, relies heavily on the autophagy machinery of the host. This response is studied intensively in epithelial cells, the target of Salmonella during gastrointestinal infections. However, little is known of the role that

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica