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K2000000

Ketoprofen

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

2-(3-Benzoylphenyl)propionic acid

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About This Item

Fórmula empírica (Notação de Hill):
C16H14O3
Número CAS:
22071-15-4
Peso molecular:
254.28
Número MDL:
MFCD00055790
Código UNSPSC:
41116107
ID de substância PubChem:
329817130
NACRES:
NA.24
Preço e disponibilidade não estão disponíveis no momento.

grau

pharmaceutical primary standard

família API

ketoprofen

fabricante/nome comercial

EDQM

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

cadeia de caracteres SMILES

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

chave InChI

DKYWVDODHFEZIM-UHFFFAOYSA-N

Informações sobre genes

human ... PTGS1(5742) , PTGS2(5743)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Ketoprofen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Non-steroidal anti-inflammatory compound that is selective for COX-1.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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Ketoprofen impurity C, European Pharmacopoeia (EP) Reference Standard

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Ketoprofen Related Compound A, United States Pharmacopeia (USP) Reference Standard

1356563

Ketoprofen Related Compound D hydrochloride, United States Pharmacopeia (USP) Reference Standard

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Ketoprofen Related Compound C, United States Pharmacopeia (USP) Reference Standard

BP668

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Ketoprofen ethyl ester, British Pharmacopoeia (BP) Reference Standard

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Ketoprofen Related Compound F, pharmaceutical secondary standard, certified reference material

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Ketoprofen Related Compound D, pharmaceutical secondary standard, certified reference material

PHR3018

Ketoprofen Related Compound C, pharmaceutical secondary standard, certified reference material

Pictogramas

Skull and crossbonesEnvironment
GHS06,GHS09

Palavra indicadora

Danger

Frases de perigo

H301,H315,H319,H400

Classificações de perigo

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Ikram Ullah Khan et al.
International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)
Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free
Yan-Ping Duan et al.
The Science of the total environment, 447, 267-273 (2013-02-09)
The occurrence and multi-phase distribution of five pharmaceutical compounds were investigated in an urban wastewater treatment plant (WWTP) receiving river by analysis of pharmaceuticals in sediment, particulate matter, conventional dissolved phase (>0.7 μm), colloidal phase (5 kDa to 0.7 μm)
Zeting Yuan et al.
International journal of pharmaceutics, 446(1-2), 191-198 (2013-02-21)
Chitosan (CS) grafted with β-cyclodextrin (CD-g-CS) nanoparticles as a new carrier for poorly water-soluble drugs has been developed. The CD-g-CS polymer is readily synthesized from chitosan and mono-6-deoxy-6-(p-toluenesulfonyl)-β-cyclodextrin. Three different degrees of substitution (DS) of β-cyclodextrin (β-CD) on CD-g-CS (9.6
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the
R Salgado et al.
Journal of hazardous materials, 244-245, 516-527 (2012-11-28)
Pharmaceutical compounds such as ketoprofen, diclofenac and atenolol are frequently detected at relatively high concentrations in secondary effluents from wastewater treatment plants. Therefore, it is important to assess their transformation kinetics and intermediates in subsequent disinfection processes, such as direct
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