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D4911

Sigma-Aldrich

Sulfato de dextrana

mol wt 6,500-10,000

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About This Item

Número CAS:
9011-18-1
Número MDL:
MFCD00081551
Código UNSPSC:
12352201
NACRES:
NA.21

fonte biológica

bacterial (Leuconostoc)

Nível de qualidade

100

forma

powder

peso molecular

6,500-10,000

composição

Sulfur Content, 16.0-22.0%

cor

white to light yellow

faixa de pH útil

6.0-8 (10 g/L)

solubilidade

H2O: 100 mg/mL

temperatura de armazenamento

room temp

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Descrição geral

Dextran sulfate is a sulfated polysaccharide, which is negatively charged. It is produced by the esterification of dextran with chlorosulphonic acid. Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli. It is a ribonuclease inhibitor. Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.

Aplicação

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
  • for RNA sequential probing of targets (SPOTs) imaging(61)
  • as a component of 1% injection buffer(62)

Outras notas

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
0000323978
MKCW1248
0000323978
MKCV2395
MKCV4164

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Dextran Sulfate, Sodium Salt, Molecular Biology Grade

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Valter R M Lombardi et al.
Journal of biomedicine & biotechnology, 2012, 826178-826178 (2012-05-24)
One of the main treatments currently used in humans to fight cancer is chemotherapy. A huge number of compounds with antitumor activity are present in nature, and many of their derivatives are produced by microorganisms. However, the search for new
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Parisa Yousefpour et al.
International journal of nanomedicine, 6, 1487-1496 (2011-07-29)
This study deals with the preparation and investigation of a nanoscale delivery system for the anticancer drug doxorubicin (DOX) using its complexation with polyanionic carbohydrate dextran sulfate (DS). Dynamic light scattering, SEM, and zeta potential determination were used to characterize
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Protocolos

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Conteúdo relacionado

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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