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C0982

Sigma-Aldrich

Chlorpromazine hydrochloride

meets USP testing specifications

Sinônimo(s):

2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil

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About This Item

Fórmula empírica (Notação de Hill):
C17H19ClN2S · HCl
Número CAS:
69-09-0
Peso molecular:
355.33
Beilstein:
3779989
Número CE:
200-701-3
Número MDL:
MFCD00012654
Código UNSPSC:
41116107
ID de substância PubChem:
24892290
NACRES:
NA.21

fonte biológica

synthetic (organic)

Nível de qualidade

200

Agency

USP/NF
meets USP testing specifications

Ensaio

98.0-101.5% dry basis

forma

solid

pf

194-196  °C

solubilidade

water: soluble 50 g/L

aplicação(ões)

pharmaceutical (small molecule)

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

chave InChI

FBSMERQALIEGJT-UHFFFAOYSA-N

Informações sobre genes

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356)

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Aplicação

Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

Ações bioquímicas/fisiológicas

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301,H330

Classificações de perigo

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análise (COA)

Lot/Batch Number
MKCV1273
MKCR0218
MKCN4469
MKCK1042
MKCF3512

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