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Supelco

Cirsilineol

analytical standard

Sinônimo(s):

4′,5-Dihydroxy-3′,6,7-trimethoxyflavone, 6-Methoxyluteolin 3′,7-dimethyl ether, Anisomelin, Eupatrin, Fastigenin

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About This Item

Fórmula empírica (Notação de Hill):
C18H16O7
Número CAS:
41365-32-6
Peso molecular:
344.32
Beilstein:
1355108
Número MDL:
MFCD01083015
Código UNSPSC:
85151701
ID de substância PubChem:
329760578
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

Ensaio

≥95.0% (HPLC and enzymatic)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

food and beverages

Formato

neat

cadeia de caracteres SMILES

COc1cc(ccc1O)C2=CC(=O)c3c(O)c(OC)c(OC)cc3O2

InChI

1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3

chave InChI

VKOSQMWSWLZQPA-UHFFFAOYSA-N

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Descrição geral

Cirsilineol is a bioactive flavone isolated from the herb of Artemisia vestita Wall., widely used to treat a variety of inflammatory conditions such as contact dermatitis, rheumatoid arthritis and sepsis. Cirsilineol exhibits anti-proliferative activity, which is used against different cancer cells by inducing apoptosis.

Aplicação

Cirsilineol may be used as an analytical reference standard for the quantification of the analyte in vervain samples and extracts of Teucrium polium using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCF8101
BCBZ9831
BCBZ6686
BCBV8675

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Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

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Xia Sheng et al.
The Journal of pharmacy and pharmacology, 60(11), 1523-1529 (2008-10-30)
Cirsilineol (4',5-dihydroxy-3',6,7-trimethoxyflavone) is a compound isolated from the herb of Artemisia vestita Wall (Compositae). In this study, we aimed at examining the anti-proliferative activity of cirsilineol against multiple types of cancer cells and the underlying mechanisms. Cirsilineol significantly inhibited proliferation
Qi-wei Zhang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 27(1), 23-25 (2003-05-31)
To establish a quantitative method for determination of cirsilineol in Herba Artemisiae Scopariae collected in Autumn. Sample was extracted with methanol, and cleaned up with polyamide column. ODS column was used with methanol-acetonitrile-0.5% acetic acid solution (24:19:57) as mobile phase.
Yang Sun et al.
Biochemical pharmacology, 79(2), 229-238 (2009-08-25)
Regulation of signal transducer and activator of transcription (STAT) 1 signaling is being explored as a new approach to the treatment of inflammatory bowel diseases. However, few chemicals have been reported to inhibit IFN-gamma/STAT1 signaling for Crohn's disease therapy. In
[Flavones isolated from Thymus carnosus Boiss].
E Maruhenda et al.
Annales pharmaceutiques francaises, 45(6), 467-470 (1987-01-01)
HPLC and UV-spectrophotometry analysis of flavonoids in spray-dried and freez-dried extracts of Teucrium polium L.(Lamiaceae)
Stefkov G, et al.
Macedonian pharmaceutical bulletin, 47(11), 39-44 (2012)
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