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62862

Sigma-Aldrich

Dodecilsulfato de sódio

≥90% ((Assay))

Sinônimo(s):

Dodecil sulfato de sódio, Dodecilsulfato, Lauril sulfato, Lauril sulfato de sódio, SDS

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About This Item

Fórmula linear:
CH3(CH2)11OSO3Na
Número CAS:
Peso molecular:
288.38
Beilstein:
3599286
Número CE:
Número MDL:
Código UNSPSC:
12161900
eCl@ss:
39093306
ID de substância PubChem:
NACRES:
NA.21

descrição

anionic
62

Nível de qualidade

Ensaio

≥90% ((Assay))

peso molecular

288.38 g/mol

técnica(s)

LC/MS: suitable
electrophoresis: suitable
protein quantification: suitable

pf

204-207 °C (lit.)

solubilidade

water: soluble

HLB

40

cadeia de caracteres SMILES

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

chave InChI

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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Descrição geral

Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate (SLS), has an alkyl tail of 12 carbon atoms attached to a sulfate group. It is an anionic surfactant due to the negative charge of its sulfate group.

Aplicação

Sodium dodecyl sulfate has been used:

  • to prepare Chit for coating the Janus micromotors for the synthesis of magnesium (Mg)-based micromotors
  • as a component in low salt lysis buffer to lyse the edible bird’s nest (EBN) treated cells for western blot analysis
  • in the preparation of decellularizing solution to scale down and decellularize skin fragments
Detergente aniônico

Ações bioquímicas/fisiológicas

Sodium dodecyl sulfate (SDS) is frequently used as an ingredient in a wide range of products, including pharmaceuticals, and product formulations. It is broadly used in several applications including electrophoresis for the separation of proteins and as an organic template for preparing periodic mesoporous organosilica nanospheres. SDS is also used in the solubilization of proteins and lipids, as well as drugs, dispersion of functionalized carbon nanotubes and graphene sheets, and gas hydrate formation. It is commonly used for the quick disruption of biological membranes. Due to its ability to disrupt the tissue architecture, SDS is preferred in several nucleic acid purification reagents. SDS has very low solubility in high salt, and chaotropic solutions and is readily precipitable in the presence of potassium salts, so it is usually not added to guanidinium buffers.

Características e benefícios

  • Assay: ≥90%
  • Suitable for LC/MS, electrophoresis, and protein quantification
  • Inhibits RNase and deoxyribonuclease (DNase) activity

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

4.1B - Flammable solid hazardous materials

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

338.0 °F

Ponto de fulgor (°C)

170 °C

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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