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32409

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Nicarbazin

VETRANAL®, analytical standard

Sinônimo(s):

N,N′-bis(4-Nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone

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About This Item

Fórmula empírica (Notação de Hill):
C13H10N4O5 · C6H8N2O
Número CAS:
330-95-0
Peso molecular:
426.38
Número CE:
206-359-1
Número MDL:
MFCD00867204
Código UNSPSC:
41116107
ID de substância PubChem:
329754190
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

clinical testing

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cc1cc(C)nc(O)n1.[O-][N+](=O)c2ccc(NC(=O)Nc3ccc(cc3)[N+]([O-])=O)cc2

InChI

1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9)

chave InChI

UKHWDRMMMYWSFL-UHFFFAOYSA-N

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Descrição geral

Nicarbazin, an anti-coccidial drug, is an equimolar mixture of 4,4′-dinitrocarbanilide (DNC) and 2-hydroxy-4,6-dimethylpyrimidine (HDP). It is used for prophylactic treatment of coccidiosis in poultry birds.

Aplicação

Nicarbazin may be used as a reference standard for the determination of nicarbazin residues in samples of chicken tissues, poultry feed, eggs and litter by high performance liquid chromatography (HPLC) method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Atenção

store under Argon

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

produto relacionado

Nº do produto
Descrição
Preços

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

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Certificados de análise (COA)

Lot/Batch Number
BCCK4402
BCCH5923
BCCF9120
BCBZ8824
BCBR5688V

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Efficient HPLC method for the determination of nicarbazin, as dinitrocarbanilide in broiler liver.
Capurro E, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 822(1-2), 154-159 (2005)
G F Mathis et al.
Veterinary parasitology, 121(1-2), 1-9 (2004-04-28)
A 56-day floor pen study was conducted to determine the appropriate time to administer toltrazuril (Baycox) (TOL) for control of coccidiosis in broiler chickens. Litter was seeded with field strains of Eimeria acervulina, Eimeria maxima and Eimeria tenella. On Days
Surface plasmon resonance biosensor screening of poultry liver and eggs for nicarbazin residues.
Mccarney B, et al.
Analytica Chimica Acta, 483(1-2), 165-169 (2003)
V Gaudin et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(23), 2358-2362 (2009-04-07)
Nicarbazin, a coccidiostat, is used as a feed additive in poultry but not in laying hens. Feed contamination may however occur resulting in residues being present in eggs. As a Maximum Residue Limit (MRL) does not exist for nicarbazin residues
Martin Danaher et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25(1), 32-40 (2007-10-25)
A survey was carried out on the occurrence of dinitrocarbanilide (DNC), the marker residue for nicarbazin, in poultry produced in Ireland during 2002-2004. Liver (n = 736) and breast muscle samples (n = 342) were tested. DNC residues were found
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