475914

Nystatin

from Streptomyces noursei, ≥95% (sum of two peaks, HPLC), solid, antifungal antibiotic, Calbiochem^®

• Sinônimo(s): Nystatin, Streptomyces noursei, Mycostatin
• Fórmula empírica (Notação de Hill): C₄₇H₇₅NO₁₇
• Número CAS: 1400-61-9
• Peso molecular: 926.09
• Número MDL: MFCD25541651
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• product name: Nystatin, Streptomyces noursei, A polyene antifungal antibiotic effective against yeast and mycoplasma.
• Nível de qualidade: 100
• Ensaio: ≥95% (sum of two peaks, HPLC)
• forma: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; protect from light
• cor: off-white to yellow
• solubilidade: DMSO: 50 mg/mL
• Condições de expedição: ambient
• temperatura de armazenamento: 2-8°C
• InChI: 1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31?,32?,33?,34?,35?,36?,37?,38?,40?,41-,42+,43+,44-,46+,47+/m0/s1
• chave InChI: VQOXZBDYSJBXMA-RKEBNKJGSA-N

Descrição

Descrição geral

A polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation selective ionophore that exhibits selectivity for Na⁺. Increases the activity of the Na⁺-K⁺ pump. Suggested concentration is 50 µg/ml.

A polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation-selective ionophore that exhibits selectivity for Na⁺. Increases the activity of Na⁺ - K⁺ pump.

Ações bioquímicas/fisiológicas

Potency: ≥3000 units/mg (anhydrous).

Advertência

Toxicity: Standard Handling (A)

Outras notas

Gruwel, M.L., et al. 1995. Am J. Physiol.268, H351.
Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol.4, 1855.
Skolink, P.R., et al. 1989. J. Infect. Dis.160, 1056.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable