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475820

Millipore

Mitomycin C, Streptomyces caespitosus, Carrier-Free

Antibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastric cancer cells.

Sinônimo(s):

Mitomycin C, Streptomyces caespitosus, Carrier-Free, Mitocin C, MMC

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About This Item

Fórmula empírica (Notação de Hill):
C15H18N4O5
Número CAS:
50-07-7
Peso molecular:
334.33
Número MDL:
MFCD00078109
Código UNSPSC:
12352200
Preço e disponibilidade não estão disponíveis no momento.

Nível de qualidade

100

Ensaio

≥95% (HPLC)

Formulário

solid

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze
protect from light

cor

purple

solubilidade

water: <1 mg/mL
methanol: 5 mg/mL

Condições de expedição

ambient

temperatura de armazenamento

2-8°C

InChI

1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1

chave InChI

NWIBSHFKIJFRCO-WUDYKRTCSA-N

Descrição geral

Antibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastic cancer cells. Blocks the cell cycle at the G2 phase.
Antibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastric cancer cells. Blocks the cell cycle at the G2 phase. Potency: ≥970 µg/mg.

Ações bioquímicas/fisiológicas

Potency: ≥ 970 μg/mg mitomycin C

Advertência

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Reconstituição

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Outras notas

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Kryt, F.A., et al. 1996. Blood 89, 938.
Schwartz, G.K., et al. 1995. J. Natl. Cancer Inst. 87, 1394.
Folnan, R.S., 1993. Oncology 50, 24.
Tomasz, M., et al. 1987. Science 235, 1204.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Frases de perigo

H300,H351

Classificações de perigo

Acute Tox. 2 Oral - Carc. 2

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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