203350
Blasticidin S hydrochloride
from Streptomyces griseochromogenes, ≥98% (HPLC), powder, protein syntheis inhibitor, Calbiochem®
Sinônimo(s):
Blasticidin S, Hydrochloride, Streptomyces griseochromogenes
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About This Item
Fórmula empírica (Notação de Hill):
C17H26N8O5 · xHCl
Número CAS:
Peso molecular:
422.44 (free base basis)
Número MDL:
Código UNSPSC:
51286700
NACRES:
NA.77
Produtos recomendados
product name
Blasticidin S, Hydrochloride, Streptomyces griseochromogenes,
Ensaio
≥98% (HPLC)
Nível de qualidade
forma
powder
fabricante/nome comercial
Calbiochem®
condição de armazenamento
OK to freeze
desiccated (hygroscopic)
cor
white to off-white
Condições de expedição
ambient
temperatura de armazenamento
2-8°C
Descrição geral
Nucleoside antibiotic that specifically inhibits protein synthesis in both prokaryotes and eukaryotes. Suitable for selection of cells carrying plasmids conferring blasticidin resistance. Blasticidin resistance is conferred by the blasticidin S deaminase genes (bsr from Bacillus cereus or BSD from Aspergillus terreus), whose products convert blasticidin S to a non-toxic deaminohydroxy derivative.
Nucleoside antibiotic that specifically inhibits protein synthesis in both prokaryotes and eukaryotes. Suitable for use as a dominant selectable marker in conjunction with blasticidin S resistant plasmids. Blasticidin S resistance is conferred by the blasticidin S deaminase gene (bcr), which converts blastisidin S to a nontoxic deaminohydroxy derivative.
Ações bioquímicas/fisiológicas
Primary Target
protein synthesis
protein synthesis
Advertência
Toxicity: Highly Toxic (H)
Reconstituição
Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions (pH ≤7) are stable for up to 1 year at -20°C. Avoid alkaline pH. Do not subject to freeze/thaw cycles; upon thawing any aliquots, discard the unused portion.
Outras notas
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Kimura, M., et al. 1994. Biochim. Biophys. Acta1219, 653.
Kimura, M., et al. 1994, Mol. Gen. Genet.242, 121.
Kojima, N., et al. 1994. J. Biol. Chem.269, 30451.
Kudo, T., et al. 1994. J. Immunol. Methods177, 17.
Sutoh, K. 1993. Plasmid30, 150.
Izumi, M., et al. 1991. Exp. Cell Res.197, 229.
Yamaguchi, H., et al. 1965. J. Biol. Chem.57, 667.
Takeuchi, S., et al. 1958. J. Antibiot.11, 1.
Kimura, M., et al. 1994, Mol. Gen. Genet.242, 121.
Kojima, N., et al. 1994. J. Biol. Chem.269, 30451.
Kudo, T., et al. 1994. J. Immunol. Methods177, 17.
Sutoh, K. 1993. Plasmid30, 150.
Izumi, M., et al. 1991. Exp. Cell Res.197, 229.
Yamaguchi, H., et al. 1965. J. Biol. Chem.57, 667.
Takeuchi, S., et al. 1958. J. Antibiot.11, 1.
Informações legais
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 1 Oral
Código de classe de armazenamento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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