1.00164

Ácido bórico

cryst., EMPROVE^® API, Ph. Eur., BP, NF

• Sinônimo(s): Orthoboric acid, Trihydroxidoboron
• Fórmula linear: H₃BO₃
• Número CAS: 10043-35-3
• Peso molecular: 61.83
• Número MDL: MFCD00011337
• Código UNSPSC: 12352106
• Número do índice EC: 233-139-2

Propriedades

• Agency: BP; NF; Ph. Eur.
• Nível de qualidade: 600
• pressão de vapor: 2.6 mmHg ( 20 °C)
• linha de produto: EMPROVE^® API
• Ensaio: 99.5-100.5% (alkalimetric)
• Formulário: solid
• potência: 2660 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• pf: 160 °C (dec.) (lit.)
• solubilidade: 49.2 g/L
• densidade: 1.489 g/cm³ at 23 °C
• densidade volumétrica: 400‑600 kg/m³
• traços de ânion: sulfate (SO₄^2-): ≤0.04%
• traços de cátion: As: ≤0.0001%; heavy metals (as Pb): ≤0.0015%
• aplicação(ões): liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation
• temperatura de armazenamento: 2-25°C
• cadeia de caracteres SMILES: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• chave InChI: KGBXLFKZBHKPEV-UHFFFAOYSA-N

Descrição

Descrição geral

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicação

Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

Informações legais

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H360FD
• Declarações de precaução: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classificações de perigo: Repr. 1B
• Código de classe de armazenamento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable