Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

05-730

Sigma-Aldrich

Anti-STEP Antibody, clone 23E5

clone 23E5, Upstate®, from mouse

Sinônimo(s):

Neural-specific protein-tyrosine phosphatase, PTPN5

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100

forma do anticorpo

purified antibody

tipo de produto de anticorpo

primary antibodies

clone

23E5, monoclonal

reatividade de espécies

mouse, rat, human

fabricante/nome comercial

Upstate®

técnica(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

nº de adesão NCBI

NM_019253

nº de adesão UniProt

P54829

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... PTPN5(84867)

Especificidade

STEP61, STEP46, STEP38 and STEP20

Imunogênio

Peptide corresponding to amino acids 57-74 of rat STEP46

Aplicação

Anti-STEP Antibody, clone 23E5 is an antibody against STEP for use in IP, WB, IH.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Neurodegenerative Diseases

Qualidade

routinely evaluated by immunoblot on in RIPA lysates from whole rat brain preparations

Descrição-alvo

~64-66 (doublet) & 46

forma física

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Purified

Armazenamento e estabilidade

2 years at -20°C

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Ferramenta de seleção de produtos.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures.
Lombroso, P J, et al.
The Journal of Neuroscience, 13, 3064-3074 (1993)
Jun Chen et al.
The European journal of neuroscience, 29(2), 287-306 (2009-02-10)
Although the mechanisms underlying striatal neurodegeneration are poorly understood, we have shown that striatal pathogenesis may be initiated by high synaptic levels of extracellular dopamine (DA). Here we investigated in rat striatal primary neurons the mobilization of the mitogen-activated protein
Daniel Radzicki et al.
Hippocampus, 33(3), 133-149 (2023-02-11)
Hippocampal area CA2 is a molecularly and functionally distinct region of the hippocampus that has classically been defined as the area with large pyramidal neurons lacking input from the dentate gyrus and the thorny excrescences (TEs) characteristic of CA3 neurons.
Serena M Dudek et al.
Hippocampus, 33(6), 700-711 (2023-05-09)
Since 1959, the Russian Farm-Fox study has bred foxes to be either tame or, more recently, aggressive, and scientists have used them to gain insight into the brain structures associated with these behavioral features. In mice, hippocampal area CA2 has
Sofía Espinoza et al.
BMC biology, 18(1), 164-164 (2020-11-08)
Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate with this dysfunction and have neuropathogenic effects that are mediated by cross-reacting with neuronal surface P antigen (NSPA) protein. Elucidating the
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica