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LM1701

Avanti

17:1 Lyso PA

Avanti Research™ - A Croda Brand

Sinônimo(s):

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt)

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About This Item

Fórmula empírica (Notação de Hill):
C20H42NO7P
Número CAS:
1246298-35-0
Peso molecular:
439.52
Código UNSPSC:
51191904
NACRES:
NA.25

forma

methanol solution

embalagem

pkg of 1 × 1 mL (LM1701-1EA)

fabricante/nome comercial

Avanti Research™ - A Croda Brand

concentração

~10 μg/mL (Refer to C of A for lot specific concentration. )

aplicação(ões)

lipidomics
metabolomics

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+]

Descrição geral

Lysophosphatidic acid (Lyso PA) is a water-soluble lipid, localized to all cells and tissues in mammals.

Aplicação

17:1 Lyso PA or 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt) has been used as an internal standard for unsaturated lysophosphatidic acid (LPA) ester and cyclic LPA ethers in reversed-phase ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS/MS).

Ações bioquímicas/fisiológicas

Lysophosphatidic acid (Lyso PA) is considered as a biological modulator of various functions in the cell. It is a potent signaling molecule with growth-factor-like actions. Lyso PA regulates cell proliferation, survival, cytoskeletal modification and calcium influx. It is associated with smooth-muscle contraction and platelet aggregation. It is also known to regulate blood pressure. Lyso PA possess extensive biological actions and is involved in the progression of several human cancer.

Embalagem

2 mL Amber Glass Sealed Ampule (LM1701-1EA)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

geralmente comprado junto com este produto

Nº do produto
Descrição
Preços

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Oleoyl-L-α-lysophosphatidic acid sodium salt ≥98%, solid

Sigma-Aldrich

L7260

Oleoyl-L-α-lysophosphatidic acid sodium salt

Gordon B Mills et al.
Nature reviews. Cancer, 3(8), 582-591 (2003-08-02)
The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation, migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA production, receptor expression and signalling probably contribute to cancer initiation, progression and metastasis. The recent identification of ecto-enzymes that
T Sasagawa et al.
Journal of nutritional science and vitaminology, 44(6), 809-818 (1999-04-10)
Abnormal phospholipid metabolism may play an important role in the progression of atherosclerosis in renal failure. We analyzed plasma phospholipid and lysophospholipid contents and fatty acid composition in the phospholipids of 18 patients with renal failure on hemodialysis (HD) and
Mu-En Lin et al.
Prostaglandins & other lipid mediators, 91(3-4), 130-138 (2010-03-25)
Lysophosphatidic acid (LPA), a water-soluble phospholipid, has gained significant attention in recent years since the discovery that it acts as a potent signaling molecule with wide-ranging effects on many different target tissues. There are currently five identified G protein-coupled receptors
Andrew Draganski et al.
The journal of sexual medicine, 15(5), 645-653 (2018-04-28)
Curcumin, a naturally occurring anti-inflammatory compound, has shown promise in pre-clinical studies to treat erectile dysfunction (ED) associated with type-1 diabetes. However, poor bioavailability following oral administration limits its efficacy. The present study evaluated the potential of topical application of

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