857127P

17:0 Lyso PA

1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

• Sinônimo(s): heptadecanoyl lysophosphatidic acid; 1-heptadecanoyl-sn-glycero-3-phosphate (sodium salt); PA(17:0/0:0); 17:0 LPA; 110679
• Fórmula empírica (Notação de Hill): C₂₀H₄₀O₇PNa
• Número CAS: 799268-66-9
• Peso molecular: 446.49
• Número MDL: MFCD00672604
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• Ensaio: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Formulário: powder
• embalagem: pkg of 1 × 25 mg (857127P-25mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 857127P
• tipo de lipídio: phospholipids; cardiolipins
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100 nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells.[1]

Aplicação

17:0 Lyso PA is suitable to use as an internal standard:

• for mass spectrometric determination of lysophosphatidic acid molecular species in mouse peritoneal macrophages[2]
• in the quantification of the lipid species released from extended synaptotagmin 2 (E-SYT2) expressed in mammalian cells by liquid chromatography with tandem mass spectrometry (LC-MS/MS)[3]
• for the extraction of lipids from brain homogenate[4]
• to extract lipids from the stomach washing solution for the determination of lysophosphatidic acid in a mouse stomach fluid[5]

Ações bioquímicas/fisiológicas

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).[1]

Embalagem

5 mL Amber Glass Screw Cap Vial (857127P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): No data available
• Ponto de fulgor (°C): No data available