791640C
Avanti
15:0-18:1-d7-PG
Avanti Research™ - A Croda Brand 791640C
Sinônimo(s):
1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt)
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1 MG
R$ 1.094,00
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1 MG
R$ 1.094,00
About This Item
Fórmula empírica (Notação de Hill):
C39H67D7NaO10 P
Número CAS:
Peso molecular:
764.01
Número MDL:
Código UNSPSC:
41141825
NACRES:
NA.25
Produtos recomendados
Ensaio
>99% (TLC)
Formulário
liquid
embalagem
pkg of 1 × 1 mL (791640C-1mg)
fabricante/nome comercial
Avanti Research™ - A Croda Brand 791640C
concentração
1 mg/mL (791640C-1mg)
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
Descrição geral
15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] is a deuterated phospholipid. The lipid comprises phosphatidylglycerol attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylglycerol is anionic phospholipid and is associated with thylakoids, microsomal and mitochondrial membrane.[1]
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
Aplicação
15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt),) has been used:
- as a component of extraction solvent for lipid isolation from biological samples [2]
- as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis[3]
- as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis[4]
Ações bioquímicas/fisiológicas
Phosphatidylglycerol (PG) plays a key role in photosynthesis. Cardiolipin is synthesized from PG. PG mediates many mitochondrial functions.[5]
Embalagem
2 mL Amber Glass Sealed Ampule (791640C-1mg)
Informações legais
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
geralmente comprado junto com este produto
Nº do produto
Descrição
Preços
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
Órgãos-alvo
Central nervous system, Liver,Kidney
Código de classe de armazenamento
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
does not flash
Ponto de fulgor (°C)
does not flash
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Lot/Batch Number
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Shin-Ya Morita et al.
Scientific reports, 5, 11737-11737 (2015-07-01)
Phosphatidylglycerol (PG) and cardiolipin (CL) are synthesized in mitochondria and regulate numerous biological functions. In this study, a novel fluorometric method was developed for measuring PG and CL using combinations of specific enzymes and Amplex Red. This assay quantified the
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Originally Lipid droplets (LDs) were considered as being droplets for lipid storage only. Increasing evidence, however, demonstrates that LDs fulfill a pleiotropy of additional functions. Among them is the modulation of protein as well as lipid homeostasis. Under unfavorable pro-oxidative
Tong Liu et al.
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Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
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Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
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