700001P

DC-Cholesterol HCl

Avanti Research^™ - A Croda Brand 700001P, powder

• Sinônimo(s): 3β-[N-(N′,N′-dimethylaminoethane)-carbamoyl]cholesterol hydrochloride
• Fórmula empírica (Notação de Hill): C₃₂H₅₇N₂O₂Cl
• Número CAS: 166023-21-8
• Peso molecular: 537.26
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: powder
• embalagem: pkg of 1 × 1 g (700001P-1g); pkg of 1 × 200 mg (700001P-200mg); pkg of 1 × 25 mg (700001P-25mg); pkg of 1 × 500 mg (700001P-500mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 700001P
• aplicação(ões): vaccine development
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [H][C@](C1)(OC(NCC[N+](C)([H])C)=O)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](C)CCCC(C)C.[Cl-]
• InChI: 1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H
• chave InChI: ISXSJGHXHUZXNF-UHFFFAOYSA-N

Descrição

Descrição geral

DC-Cholesterol HCl is a cholesterol derivative and a cationic lipid with a head group and linker moiety.

DC-Cholesterol HCl is a sterol-based transfection reagent.

Aplicação

DC-Cholesterol HCl is suitable:

• for the preparation of ultrasound cationic microbubbles
• to prepare liposomes
• for the preparation of L-glutathione (GSH), loaded proliposomes

DC-Cholesterol HCl may be used in the preparation of colloidal dispersions for transmission electron microscopy studies. It may also be used in liposome preparation for assessing hexokinase activity, poly (lactic-coglycolicacid) loading and in mRNA transfection studies.

Ações bioquímicas/fisiológicas

DC-Cholesterol is an effective transfection agent and a liposome reagent. Liposome of DC-Cholesterol with dioleoylphosphatidylethanolamine (DOPE) are efficient for DNA transfection. It imparts positive surface charge to the microbubbles for ultra sound based transfection of clustered regularly interspaced short palindromic repeats (CRISPRs).

DC-cholesterol is a cationic lipid, known to be the most efficient in gene transfection study.

Embalagem

20 mL Clear Glass Screw Cap Vial (700001P-1g)

20 mL Clear Glass Screw Cap Vial (700001P-500mg)

5 mL Amber Glass Screw Cap Vial (700001P-200mg)

5 mL Amber Glass Screw Cap Vial (700001P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable