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Documentos Principais

861448

Sigma-Aldrich

8-Azaguanine

98%

Sinônimo(s):

2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo

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About This Item

Fórmula empírica (Notação de Hill):
C4H4N6O
Número CAS:
Peso molecular:
152.11
Beilstein:
171098
Número CE:
Número MDL:
Código UNSPSC:
12352200

Ensaio

98%

pf

>300 °C (lit.)

cadeia de caracteres SMILES

NC1=Nc2[nH]nnc2C(=O)N1

InChI

1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)

chave InChI

LPXQRXLUHJKZIE-UHFFFAOYSA-N

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Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
Christian Pfeifle et al.
Anticancer research, 29(11), 4489-4496 (2009-12-25)
Despite improvements in the treatment of patients with Ewing family tumours (EFT) during the past decades, the prognosis for patients with advanced disease is still unsatisfying. New treatment strategies have to be developed. A hypoxanthine/aminopterin/thymidine (HAT)-sensitive EFT cell line was
Jacek Wierzchowski et al.
Nucleosides, nucleotides & nucleic acids, 24(5-7), 459-464 (2005-10-27)
Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, an excellent fluorescent/fluorogenic substrate for the synthetic pathway of the reaction, and its 9-(2-phosphonylmethoxyethyl) derivative, a bisubstrate analogue inhibitor, were carried out. The goal was to
Yan-li Wei et al.
Guang pu xue yu guang pu fen xi = Guang pu, 24(7), 862-866 (2005-03-16)
The inclusion complexes of beta-Cyclodextrin (beta-CD) and HP-beta-Cyclodextrin (HP-beta-CD) with 6-Mercaptopurine (6-MP), Azathioprine (BAN) and 8-Azaguanine (Azan) were investigated by fluorescence. Various factors affecting the formation of inclusion complexes were discussed in detail including formation time and pH effect. The
T L Bowen et al.
Journal of bacteriology, 178(9), 2521-2526 (1996-05-01)
Phosphoribosyltransferase (PRTase) and nucleoside phosphorylase (NPase) activities were detected by radiometric methods in extracts of Methanococcus voltae. Guanine PRTase activity was present at 2.7 nmol min(-1) mg of protein(-1) and had an apparent Km for guanine of 0.2 mM and

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