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Documentos Principais

769819

Sigma-Aldrich

Resomer® RG 753 H, Poly(D,L-lactide-co-glycolide)

acid terminated

Sinônimo(s):

Resomer® RG 753 H, PLGA

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About This Item

Fórmula linear:
HO[C2H4O2]n[C2H2O2]mH
Número CAS:
Número MDL:
Código UNSPSC:
12162002
NACRES:
NA.23
Preço e disponibilidade não estão disponíveis no momento.

Nível de qualidade

Formulário

amorphous

proporção de alimentação

lactide:glycolide 75:25

viscosidade

0.32-0.44 dL/g

temperatura de transição

Tg 44-55 °C

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

chave InChI

LCSKNASZPVZHEG-UHFFFAOYSA-N

Aplicação

Resomer® RG 753 H, Poly(D,L-lactide-co-glycolide) is a biodegradable and biocompatible aliphatic polyester, which can be used in the development of nano and microparticles. It is a pharmaceutical polymer, which finds potential usage in drug delivery and gene delivery. It forms a three-dimensional porous scaffold, which can be used in tissue engineering.[1][2][3][4]

Informações legais

RESOMER is a registered trademark of Evonik Rohm GmbH

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

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Visite a Biblioteca de Documentos

In vitro degradation of three-dimensional porous poly (D, L-lactide-co-glycolide) scaffolds for tissue engineering
Wu L and Ding J
Biomaterials, 25(27), 5821-5830 (2004)
Development and evaluation of novel biodegradable microspheres based on poly (d, l-lactide-co-glycolide) and poly (varepsilon-caprolactone) for controlled delivery of doxycycline in the treatment of human periodontal pocket: in vitro and in vivo studies
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 119(1), 59-68 (2007)
Nanoparticles made of fluorescence-labelled poly (L-lactide-co-glycolide): preparation, stability, and biocompatibility
Weiss B, et al.
Journal of Nanoscience and Nanotechnology, 6(9-10), 3048-3056 (2006)
Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 125(3), 193-209 (2008)

Questions

1–3 of 3 Questions  
  1. What is the solubility parameter for polymers in different solvents?

    1 answer
    1. The solubility parameters for this product have not been determined. However, this product can be solubilized in ethyl acetate, chloroform, acetone, and THF.

      Helpful?

  2. Was ist das Molekulargewicht vom Polymer?

    1 answer
    1. The molecular weight is reported on the lot-specific Certificate of Analysis. Please navigate to the ‘DOCUMENTATION’ section of the Product Detail Page to access a Certificate:
      https://www.sigmaaldrich.com/product/aldrich/769819#product-documentation

      Helpful?

  3. What is the solubility parameter for polymers in different solvents?

    1 answer
    1. The solubility parameters for this product have not been determined. However, various sources state this product can be solubilized in ethyl acetate, chloroform, acetone and THF. Please see the link below to learn more about Resomer Biodegradable Polymers: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/materials-science-and-engineering/drug-delivery/resomer

      Helpful?

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