655414

2-(2′-Di-tert-butylphosphine)biphenylpalladium(II) acetate

97%

• Sinônimo(s): Palladium, (acetato-ΚO) [2′-[bis (1,1 dimethylethyl) phosphino-ΚP] [1,1′-biphenyl]-2-yl ΚC]
• Fórmula empírica (Notação de Hill): C₂₂H₂₉O₂PPd
• Número CAS: 577971-19-8
• Peso molecular: 462.86
• Número MDL: MFCD04117716
• Código UNSPSC: 12352300
• ID de substância PubChem: 24884102
• NACRES: NA.22

Propriedades

• Ensaio: 97%
• forma: solid
• adequação da reação: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Cross Couplings; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst
• pf: 130-140 °C (dec.) (lit.)
• cadeia de caracteres SMILES: CC(=O)[Pd]1c2ccccc2-c3ccccc3[PH]1(C(C)(C)C)C(C)(C)C
• InChI: 1S/C20H26P.C2H4O2.Pd/c1-19(2,3)21(20(4,5)6)18-15-11-10-14-17(18)16-12-8-7-9-13-16;1-2(3)4;/h7-12,14-15H,1-6H3;1H3,(H,3,4);/q;;+1/p-1
• chave InChI: IEYDYAASBZOBOC-UHFFFAOYSA-M

Descrição

Descrição geral

2-(2′-Di-tert-butylphosphine)biphenylpalladium(II) acetate is a novel, air- and moisture-and thermally stable catalyst.

Aplicação

It can be used as a pre-catalyst for the amination of aryl chlorides. It can also be used to prepare N-methyl-6-heterocyclic-1-oxoisoindoline derivatives via Buchwald-Hartwig amination reaction of N-methyl-6- bromoisoindoline-1-one with different amines under microwave condition.

Precatalyst for Buchwald-Hartwig amination reaction.

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)