586579

5-Fluoro-2-oxindole

97%

• Sinônimo(s): 5-Fluoro-1,3-dihydroindol-2-one, 5-Fluoro-2,3-dihydro-2-oxoindole
• Fórmula empírica (Notação de Hill): C₈H₆FNO
• Número CAS: 56341-41-4
• Peso molecular: 151.14
• Número MDL: MFCD02179598
• Código UNSPSC: 12352100
• ID de substância PubChem: 24881126
• NACRES: NA.22

Propriedades

• Ensaio: 97%
• pf: 143-147 °C (lit.)
• cadeia de caracteres SMILES: Fc1ccc2NC(=O)Cc2c1
• InChI: 1S/C8H6FNO/c9-6-1-2-7-5(3-6)4-8(11)10-7/h1-3H,4H2,(H,10,11)
• chave InChI: DDIIYGHHUMKDGI-UHFFFAOYSA-N

Descrição

Aplicação

Reactant for preparation of:

• Glycogen synthase kinase 3 beta (GSK-3β) inhibitors
• Antitumor agents
• Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors
• Multitargeted Receptor Tyrosine Kinase Inhibitors
• Non-peptide thrombopoietin (TPO) receptor ligands
• Aurora kinase inhibitors
• Inhibitors of cyclin-dependent kinase CDK2/cyclin A
• Selective norepinephrine reuptake inhibitors
• B-cell lymphoma-extra large molecule (Bcl-XL) inhibitor Z36
• Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)