Pular para o conteúdo
Merck
Todas as fotos(3)

Documentos Principais

Visualizar Toda a Documentação

318426

Sigma-Aldrich

3,3′-Dihexyloxacarbocyanine iodide

98%

Sinônimo(s):

3-hexyl-2-[3-(3-hexyl-2(3H)benzoxazolylidene)-1-propenyl]benzoxazolium iodide

Faça loginpara ver os preços organizacionais e de contrato

Selecione um tamanho

250 MG
R$ 838,00
1 G
R$ 2.325,00

R$ 838,00

Check Cart for Availability
Solicite uma grande encomenda
Todas as fotos(3)

Selecione um tamanho

Alterar visualização
250 MG
R$ 838,00
1 G
R$ 2.325,00

About This Item

Fórmula empírica (Notação de Hill):
C29H37IN2O2
Número CAS:
53213-82-4
Peso molecular:
572.52
Beilstein:
9312562
Número MDL:
MFCD00011954
Código UNSPSC:
12171500
ID de substância PubChem:
24859130
NACRES:
NA.47

R$ 838,00

Check Cart for Availability
Solicite uma grande encomenda

Nível de qualidade

100

Ensaio

98%

Formulário

powder or chunks

técnica(s)

titration: suitable

pf

219-221 °C (lit.)

solubilidade

chloroform: 25 mg/mL, clear to slightly hazy, orange

λmax

485 nm

ε (coeficiente de extinção)

≥120000 at 483-488 nm in methanol at 0.01 g/L

fluorescência

λex 485 nm; λem 501 nm in methanol

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

[I-].CCCCCCN1\C(Oc2ccccc12)=C\C=C\c3oc4ccccc4[n+]3CCCCCC

InChI

1S/C29H37N2O2.HI/c1-3-5-7-13-22-30-24-16-9-11-18-26(24)32-28(30)20-15-21-29-31(23-14-8-6-4-2)25-17-10-12-19-27(25)33-29;/h9-12,15-21H,3-8,13-14,22-23H2,1-2H3;1H/q+1;/p-1

chave InChI

XVLXYDXJEKLXHN-UHFFFAOYSA-M

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Descrição geral

3,3′-dihexyloxacarbocyanine iodide (DiOC6) is a supravital lipophilic fluorochrome.[1][2] This cationic dye is employed to stain mitochondria[3] and endoplasmic reticulum in animal and plant cells.[1][2] In addition, it acts as a very rapid, consistent and highly selective fluorochrome for endophytic ascomycetes in plant roots and liverworts.[2] DiOC6 also facilitates the detection of different mitochondrial changes happening during early apoptosis.[3]

Aplicação

3,3′-Dihexyloxacarbocyanine iodide has been used:
  • to selectively stain endophytic ascomycetes in plant roots and liverworts[2]
  • to visualize thrombus formation and platelet aggregate[3]
  • to visualize forchlorfenuron (FCF)-induced changes in mitochondrial morphology[4]

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKBL7987V
MKBG8334V
MKBG8160V
11826MD
08024HD

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

diacetato de 2′,7′-diclorofluoresceína ≥97%

Sigma-Aldrich

D6883

diacetato de 2′,7′-diclorofluoresceína

3,3′-Diethylthiacyanine iodide Dye content ~97 %

Sigma-Aldrich

390410

3,3′-Diethylthiacyanine iodide

Growth Hormone Releasing Factor Fragment 1-29 amide human ≥97% (HPLC)

Sigma-Aldrich

G6771

Growth Hormone Releasing Factor Fragment 1-29 amide human

Mito Red suitable for fluorescence, ≥70% (HPLC)

Sigma-Aldrich

53271

Mito Red

Lys05 ≥98% (HPLC)

Sigma-Aldrich

SML2097

Lys05

Examination of living and fixed gametes and early embryos stained with supravital fluorochromes (Hoechst 33342 and 3, 3?-dihexyloxacarbocyanine iodide)
Luttmer SJ and Longo FJ
Gamete Research, 15(3), 267-283 (1986)
Microfluidic cell sorting: Towards improved biocompatibility of extracorporeal lung assist devices
Bleilevens C, et al.
Scientific reports, 8(1), 8031-8031 (2018)
Yanyan Zheng et al.
European journal of medicinal chemistry, 125, 902-913 (2016-10-22)
Emodin, a natural anthraquinone derivative isolated from Rheum palmatum L., has been demonstrated to exhibit good anti-cancer effect. In this study, a series of novel quaternary ammonium salts of emodin, anthraquinone and anthrone were synthesized and their anticancer activities were
Xueying Zhuang et al.
Mycological research, 113(Pt 4), 417-431 (2008-12-31)
Growth and organelle morphology in the wood rotting basidiomycete fungus Phanerochaete velutina were examined in Petri dishes, on agar-coated slides, and in submerged cultures, using DIC, fluorescence and four-dimensional (4-D; x,y,z,t) confocal microscopy, with several fluorescent probes. Phanerochaete is ideal
Ashlesha A Kadam et al.
Biochimica et biophysica acta, 1861(1 Pt A), 2942-2955 (2016-10-23)
Apoptosis Inducing Factor (AIF), a phylogenetically conserved mitochondrial inter-membrane space flavoprotein has an important role in caspase independent cell death. Nevertheless, AIF is also essential for cell survival. It is required for mitochondrial organization and energy metabolism. Upon apoptotic stimulation
Exibir todos os documentos relacionados

Artigos

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

Questions

  1. 本製品をクロロホルムで溶解するときの推奨プロトコルはございますでしょうか。クロロホルムは原液でしょうか。 他社の DiOC6 の説明では溶媒として DMSO も挙げられるようですが、本製品の DMSO への溶解性はいかがでしょうか。

    1 answer

    1. No formal protocol exists for dissolving this product in chloroform. The Specification Sheet and the Certificate of Analysis indicate that solubility is tested at 25 mg/mL in chloroform during quality control testing. It is suggested to dissolve up to 25 mg/mL in chloroform and mix well until the solid is dissolved.
      The chemical may be soluble in other solvents. No attempt is made during quality control to test in a range of solvents. It is certainly possible that other companies may test in DMSO or other solvents. If other companies claim DIOC6 is soluble in a particular solvent, product 318426 should also be soluble. Since the only solvent used for solubility testing is chloroform, there is no guarantee product 318426 will meet the solubility claims from other companies.

      Conn's Biological Stains, 10th Edition advises that 3,3?-Dihexyloxacarbocyanine iodide is also soluble in DMSO and methanol. No exact values are provided for the solubility of DiOC6 in either DMSO or methanol. No solubility data is available from PubChem, The Merck Index or Martindale The Extra Pharmacopeia.

      Helpful?

Reviews

No rating value

Active Filters

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica