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Merck
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178950

Sigma-Aldrich

Methanesulfonyl fluoride

98%

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About This Item

Fórmula linear:
CH3SO2F
Número CAS:
Peso molecular:
98.10
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:

Ensaio

98%

adequação da reação

reaction type: click chemistry

pb

123-124 °C (lit.)

densidade

1.427 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

CS(F)(=O)=O

InChI

1S/CH3FO2S/c1-5(2,3)4/h1H3

chave InChI

KNWQLFOXPQZGPX-UHFFFAOYSA-N

Descrição geral

Methanesulfonyl fluoride is an anticholinesterase (antiChEs), used to treat Alzheimer′s disease. It is a thrombin inhibitor.

Pictogramas

Skull and crossbonesCorrosion

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 2 Oral - Skin Corr. 1B

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Navid Jamali et al.
Reproductive sciences (Thousand Oaks, Calif.), 28(3), 683-692 (2020-11-04)
Endometriosis, as the leading cause of infertility, is attributed to oxidative stress, inflammation, and autophagy dysregulation. This study was conducted to evaluate the effect of quercetin and metformin, alone or in combination, on the ectopic and eutopic endometrial tissues in
M Zorko et al.
Biochemical pharmacology, 35(14), 2287-2296 (1986-07-15)
The binding of D-tubocurarine (TC) to acetylcholinesterase (AChE) was studied using different methods of enzyme kinetics. The main results are as follows. TC reversibly inhibits the hydrolysis of different substrates of AChE with three different inhibition constants (Ki1 = 7.0
D H Malin et al.
Neurobiology of aging, 12(2), 181-183 (1991-03-01)
In previous studies, 18-month-old rats have shown no significant retention 24 hours after the single acquisition trial in a one-trial discriminative reward learning task. In the present study, ten 18-month-old rats pretreated with 0.5 mg/kg MSF IP showed significantly better
P Masson et al.
Biochimica et biophysica acta, 869(3), 304-313 (1986-02-14)
In order to determine whether a structural modification at the active center of cholinesterase may alter the conformational stability of the enzyme we compared the urea-induced unfolding of the tetrameric form of non-inhibited and irreversibly inhibited human plasma cholinesterase (acylcholine
D H Malin et al.
Neurobiology of aging, 14(4), 393-395 (1993-07-01)
Aged (24-month-old) rats were treated chronically with methanesulfonyl fluoride (MSF), an acetylcholinesterase (AChE) inhibitor with selectivity for central nervous system AChE, or with injection vehicle alone. Twelve 0.22 mg/kg IP injections were given over 4 weeks. MSF rats showed significantly

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