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15404

Sigma-Aldrich

N-Boc-1,4-butanediamine

≥97.0% (GC/NT)

Sinônimo(s):

N-Boc-1,4-diaminobutane, tert-Butyl N-(4-aminobutyl)carbamate

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5 ML
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About This Item

Fórmula linear:
(CH3)3COCONH(CH2)4NH2
Número CAS:
68076-36-8
Peso molecular:
188.27
Beilstein:
1937878
Número MDL:
MFCD00210019
Código UNSPSC:
12352116
ID de substância PubChem:
57647412
NACRES:
NA.22

R$ 927,00

Previsão de entrega em26 de maio de 2025

Solicite uma grande encomenda

Nível de qualidade

100

Ensaio

≥97.0% (GC/NT)

adequação da reação

reagent type: cross-linking reagent

índice de refração

n20/D 1.460

densidade

0.984 g/mL at 20 °C (lit.)

grupo funcional

Boc
amine

cadeia de caracteres SMILES

NCCCCNC(OC(C)(C)C)=O

InChI

1S/C9H20N2O2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7,10H2,1-3H3,(H,11,12)

chave InChI

ZFQWJXFJJZUVPI-UHFFFAOYSA-N

Categorias relacionadas

Aplicação

  • Carboxy-Silane Coated Iron Oxide Nanoparticles: Details the application of N-Boc-1,4-butanediamine in modifying iron oxide nanoparticles for imaging and drug delivery (D Stanicki, S Boutry, S Laurent, et al., 2014). Access the article.

Outras notas

Preparation of pharmacologically active compounds.[1][2] Preparation of spermidine analogues.[3] Introduction of a C4-spacer.[4][5]

Pictogramas

Corrosion
GHS05

Palavra indicadora

Danger

Frases de perigo

H314

Classificações de perigo

Skin Corr. 1B

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

228.2 °F - closed cup

Ponto de fulgor (°C)

109.0 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificados de análise (COA)

Lot/Batch Number
015906/2
062192/1
015906/1
010796/1
047234/1

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N-Boc-4,7,10-trioxa-1,13-tridecanediamine ≥95.0% (NT)

Sigma-Aldrich

93113

N-Boc-4,7,10-trioxa-1,13-tridecanediamine

Y Shai et al.
Biochemistry, 28(11), 4801-4806 (1989-05-30)
In the present study we synthesize 18F-labeled insulin of high specific radioactivity. A new prosthetic group methodology, in which [18F]fluoride displaces a bromide group of 4-(bromomethyl)-benzoylamine intermediates, was used. The 4-(fluoromethyl)benzoyl product was chemically stable. 18F-Labeled insulin retains the essential
Regina Holm et al.
Macromolecular rapid communications, 36(23), 2083-2091 (2015-09-08)
In this work, the synthesis of polypeptoid-block-polypeptide copolymers (block copolypept(o)ides) based on bifunctional initiators is described, which introduces a distinct chemical entity at the connection between both blocks. With a view towards redox-sensitive block copolypept(o)ides, a cystamine-based initiator was used
Hongyan Guo et al.
Journal of medicinal chemistry, 45(10), 2056-2063 (2002-05-03)
Several iron chelators containing alpha,beta-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferrioxamine B, acinetoferrin, and nannochelin A) and
Regina Holm et al.
Biomacromolecules, 20(1), 375-388 (2018-11-27)
The size control of nanomedicines for tumor diagnosis and therapy is of high importance, since it enables or disables deep and sufficient tumor penetration. Amphiphilic star-shaped block copolypept(o)ides offer substantial promise to precisely adjust the hydrophobic core and the hydrophilic
Shaohui Deng et al.
Science advances, 6(29), eabb4005-eabb4005 (2020-08-25)
Controlled release of CRISPR-Cas9 ribonucleoprotein (RNP) and codelivery with other drugs remain a challenge. We demonstrate controlled release of CRISPR-Cas9 RNP and codelivery with antitumor photosensitizer chlorin e6 (Ce6) using near-infrared (NIR)- and reducing agent-responsive nanoparticles in a mouse tumor
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MRT - Mono-Boc-Protection of Diamines

Mono-Boc-protected diamines are versatile building blocks for chemical synthesis. Their production is a lot more challenging than the simple reaction scheme might imply, because the Boc-anhydride reagent cannot differentiate between the two identical amino moieties in the substrate.

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