112968

Methylhydroquinone

99%

• Sinônimo(s): Toluhydroquinone
• Fórmula linear: CH₃C₆H₃-1,4-(OH)₂
• Número CAS: 95-71-6
• Peso molecular: 124.14
• Beilstein: 2041489
• Número CE: 202-443-7
• Número MDL: MFCD00002345
• Código UNSPSC: 12352100
• ID de substância PubChem: 24847123
• NACRES: NA.22

Propriedades

• Ensaio: 99%
• Formulário: solid
• temperatura de autoignição: 851 °F
• pf: 128-130 °C (lit.)
• cadeia de caracteres SMILES: Cc1cc(O)ccc1O
• InChI: 1S/C7H8O2/c1-5-4-6(8)2-3-7(5)9/h2-4,8-9H,1H3
• chave InChI: CNHDIAIOKMXOLK-UHFFFAOYSA-N

Descrição

Descrição geral

Methylhydroquinone is produced by the oxidation of o-cresol by the mutants G103S, G103S/A107G, and G103S/A107T[1].

Aplicação

Methylhydroquinone can be used as a reactant to prepare:

• A semiflexible thermotropic polyester via polycondensation reaction with 4,4′-sebacoyldioxydibenzoyl chloride.[2]
• A sesquiterpene (±)-helibisabonol A.[3]
• poly{hexakis[(methyl)(4-hydroxyphenoxy)]cyclotriphosphazene} by reacting with hexachlorocyclotriphosphazene.[4]
• 6-Hydroxy-4,7-dimethyl-2H-1-benzopyran-2-one by treating with ethyl acetoacetate in the presence of H₂SO₄ as a catalyst.[5]

Ações bioquímicas/fisiológicas

Methylhydroquinone (Toluquinol) inhibits the growth of endothelial and tumor cells in culture in the micromolar range and is a promising drug candidate in the treatment of cancer and other angiogenesis-related pathologies[6].

Informações de segurança

• Pictogramas: GHS05,GHS07,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H314,H317,H335,H410
• Declarações de precaução: P260 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classificações de perigo: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 8A - Combustible corrosive hazardous materials
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 341.6 °F - closed cup
• Ponto de fulgor (°C): 172 °C - closed cup
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves