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Merck

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

Sinônimos:
5-HT(2B), 5-HT2B
Espécies:
Human HTR2B (3357), Mouse Htr2b (15559), Rat Htr2b (29581), chicken HTR2B (395581), Zebrafish htr2b (751784), dog HTR2B (403881), cow HTR2B (407135), Horse HTR2B (100057052), domestic cat HTR2B (101095762), Domestic Rabbit HTR2B (100343392) ...Mais
ID UniProtKB:
P41595, B2R9D5, Q53TI1, Q62221, Q6P523
ID do gene:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
B175
BW 723C86, ≥98% (HPLC),
Espécies
human
M110
α-Methylserotonin maleate salt, ≥98% (HPLC),
Espécies
human
Q1004
Quipazine maleate salt, ,
Espécies
human

Small Molecule - Allosteric Modulator

Número do produto
Descrição
Espécies
D9190
DCEBIO, ≥98% (HPLC), solid,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
S006
Ketanserin (+)-tartrate salt, ≥97%, solid,
Espécies
human
C6022
Cyproheptadine hydrochloride sesquihydrate, ≥98% (TLC), solid,
Espécies
human
O111
Octoclothepin maleate salt, solid,
Espécies
human
38827
4,4′-Dimethoxytriphenylmethyl chloride, ≥97.0% (HPLC),
Espécies
rat, human
M3668
Metergoline, ,
Espécies
human, rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA012867
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
SAB4501476
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
western blot
HPA063658
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
SAB4501475
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
immunohistochemistry
western blot
AMAB91972
Monoclonal Anti-Htr2B Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14576, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Z101
Zimelidine dihydrochloride, solid,
Espécies
human

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
R0875
Reserpine, ,
Espécies
human
I119
Indatraline hydrochloride, solid,
Espécies
human
M8046
Mifepristone, ≥98%,
Espécies
human, mouse, rat

Small Molecule - Ligand

Número do produto
Descrição
Espécies
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Espécies
human

Small Molecule - Metabolite

Número do produto
Descrição
Espécies
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Espécies
human

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
M8046
Mifepristone, ≥98%,
Espécies
human, mouse, rat

Small Molecule - Precursor

Número do produto
Descrição
Espécies
H9772
5-Hydroxy-L-tryptophan, powder,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EHU052881
MISSION® esiRNA, targeting human HTR2B,
Espécies
human