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Z226181

Nucleosil® C18 HPLC-Säule

5 μm particle size, L × I.D. 25 cm × 4.6 mm

Synonym(e):

Nucleosil C18

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About This Item

UNSPSC-Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Agentur

suitable for USP L1

Qualitätsniveau

Produktlinie

Nucleosil®

Leistungsmerkmale

endcapped

Hersteller/Markenname

Nucleosil®

Kennzeichnungsgrad

15% Carbon loading

Parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

Methode(n)

HPLC: suitable

L × ID

25 cm × 4.6 mm

Oberflächenbereich

350 m2/g

Matrix

octadecyl

Aktive Matrixgruppe

C18 (octadecyl) phase

Partikelgröße

5 μm

Porengröße

100 Å

Trenntechnik

reversed phase

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Anwendung


  • A combined qualitative and quantitative method development and validation of vancomycin hydrochloride injection formulation by HPLC and UV involving quality by design.: This study by Sasikala et al. developed and validated an HPLC method using a Nucleosil® C18 column for the qualitative and quantitative analysis of vancomycin hydrochloride in injection formulations. The method demonstrated high precision and accuracy, making it suitable for quality control in pharmaceutical analysis (Sasikala et al., 2023).

  • Quantification and Validation of Stability-Indicating RP-HPLC Method for Efavirenz in Bulk and Tablet Dosage Form using Quality by Design (QbD): A Shifting Paradigm.: Gurumukhi and Bari developed a stability-indicating HPLC method for quantifying efavirenz in bulk and tablet forms, using a Nucleosil® C18 column. The study highlighted the method′s robustness and reliability, essential for ensuring the stability and efficacy of pharmaceutical products (Gurumukhi et al., 2022).

  • Purification and Product Characterization of Lipoxygenase from Opium Poppy Cultures (Papaver somniferum L.).: Holková et al. utilized a Nucleosil® C18 column in their HPLC method to purify and characterize lipoxygenase from opium poppy cultures. The research demonstrated the column′s effectiveness in isolating and analyzing plant-derived enzymes, contributing to biochemical and pharmacological studies (Holková et al., 2019).

  • Fabrication of size controlled nanocomposite based on zirconium alkoxide for enrichment of Gallic acid in biological and herbal tea samples.: Bahrani et al. developed a nanocomposite for enriching gallic acid, employing a Nucleosil® C18 column in their HPLC method to analyze biological and herbal tea samples. The study underscored the column′s role in enhancing analytical precision in complex matrices (Bahrani et al., 2018).

Empfohlene Produkte

Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Nucleosil® C18 HPLC Columns are packed with the finest commercially available silicas and bonded phases from the most recognized HPLC manufacturers in the world. The columns are tested with specially selected solutes that can be used to establish the reproducibility of retention and selectivity needed in the HPLC applications.

Rechtliche Hinweise

Nucleosil is a registered trademark of Macherey-Nagel GmbH & Co. KG

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Analysenzertifikate (COA)

Lot/Batch Number

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Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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