SRP4053

FGF-8 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Synonym(e): AIGF, FGF-8b, FGF8, Fibroblast Growth Factor-8, HBGF
• MDL-Nummer: MFCD01867043
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥95% (SDS-PAGE)
• Form: lyophilized
• Wirksamkeit: ≥2x10^6 units/mg
• Mol-Gew.: ~22.4 kDa
• Verpackung: pkg of 25 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Verunreinigungen: endotoxin, tested
• NCBI-Hinterlegungsnummer: NM_006119
• UniProt-Hinterlegungsnummer: P55075
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... FGF8(2253)

Beschreibung

Allgemeine Beschreibung

Fibroblast growth factor-8 (FGF-8) is also known as androgen-induced growth factor (AIGF). It is a heparin-binding growth factor. The gene encoding this protein is localized on human chromosome 10.[1] Recombinant human FGF-8 is a 22.4kDa protein containing 193 amino acid residues.

Biochem./physiol. Wirkung

Fibroblast growth factor-8 (FGF-8) stimulates the proliferation and activation of cells that express the FGF receptors. It has a role in embryogenesis. FGF8b, an isoform of FGF-8, is expressed in prostate cancer.[2][1]

Physikalische Form

Lyophilized in 10 mM Tris, pH 8.0 plus 75 mM NaCl. The protein may appear as a haze or film, which may not be seen at the bottom of the vial.

Rekonstituierung

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.1-1 mg/mL. This solution can be diluted into other aqueous buffers.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable