SML3260

Stannsoporfin

≥98% (HPLC)

• Synonym(e): B 992, Dichloro[7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24]-stannate(2-) (OC-6-13)-dihydrogen, SnMP, Stanate, Tin mesoporphyrin
• Empirische Formel (Hill-System): C₃₄H₃₆Cl₂N₄O₄Sn
• CAS-Nummer: 106344-20-1
• Molekulargewicht: 754.29
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: , Faint brown to dark red
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: CC1=C(CCC(O)=O)/C2=C/C3=N/C(C(C)=C3CCC(O)=O)=C\C4=C(CC)C(C)=C(/C=C5N=C(C(C)=C\5CC)/C=C1\N26)N4[Sn]6(Cl)Cl
• InChI: 1S/C34H38N4O4.2ClH.Sn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;;/h13-16H,7-12H2,1-6H3,(H4,35,36,37,38,39,40,41,42);2*1H;/q;;;+4/p-4/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;;
• InChIKey: LLDZJTIZVZFNCM-UHEVNVKKSA-J

Beschreibung

Biochem./physiol. Wirkung

Stannsoporfin is a potent inhibitor of heme oxygenase 1 (HO-1) and heme oxygenase 2 (HO-2). It inhibits hepatic HO and controls serum levels of bilirubin in infants. Stannsoporfin potently inhibits myeloid HO-1 in tumors. It inhibits immune suppression of chemotherapy-elicited CD8+ T cells. Stannsoporfin concurrently administer with 5-Fluoro uracil produces immediate tumor regression in mice model of breast tumor.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable