SMB01077

Poliothyrsoside

≥85% (LC/MS-ELSD)

• Synonym(e): Nigracin
• Empirische Formel (Hill-System): C₂₀H₂₂O₉
• CAS-Nummer: 18463-25-7
• Molekulargewicht: 406.38
• MDL-Nummer: MFCD20260826
• UNSPSC-Code: 12352205
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: plant
• Assay: ≥85% (LC/MS-ELSD)
• Form: solid
• Mol-Gew.: 406.38
• Anwendung(en): metabolomics; vitamins, nutraceuticals, and natural products
• Lagertemp.: −20°C
• SMILES String: O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC(=O)c3ccccc3)O)O)O)Oc2c(cc(cc2)O)CO
• InChI: 1S/C20H22O9/c21-9-12-8-13(22)6-7-14(12)28-20-18(25)17(24)16(23)15(29-20)10-27-19(26)11-4-2-1-3-5-11/h1-8,15-18,20-25H,9-10H2/t15-,16-,17+,18-,20-/m1/s1
• InChIKey: FLROYCKIIJCTDY-BFMVXSJESA-N

Beschreibung

Allgemeine Beschreibung

Poliothyrsoside, also known as Nigracin, is a phenolic glycoside compound commonly found in plants such as Flacourtia indica, Loxocalyx urticifolius, Hydnocarpus annamensis, Xylosma flexuosa, Poliothyrsis sinensis, and Scolopia spinosa. Existing research suggests that this plant-derived metabolite exerts various biological activities, antioxidant, antidiabetic, anti-alzheimers and antiplasmodial properties.

Anwendung

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Biochem./physiol. Wirkung

Poliothyrsoside is a pyruvic transaminase inhibitor known for its insulin-sensitizing effects in cell culture. Additionally, it exhibits anti-diabetic properties by inhibiting acetyl-CoA carboxylase, ultimately enhancing insulin sensitivity and lowering blood glucose levels in diabetic mice. This compound also serves as a lactate dehydrogenase inhibitor and demonstrates antidepressant-like actions, along with effectiveness against Alzheimer′s disease. In vitro studies have further revealed Poliothyrsoside′s capacity to inhibit virus production and exhibit antiviral activity against HIV-1.

Leistungsmerkmale und Vorteile

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Sonstige Hinweise

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable