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Merck

G8279

Sigma-Aldrich

Guajak-Eukalyptus

crude colorimetric peroxidase substrate

Synonym(e):

Guaiac, Guaiacum, Resin guaiac

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About This Item

CAS-Nummer:
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201

Form

powder

mp (Schmelzpunkt)

85 °C (dec.) (lit.)

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Anwendung

Gum guaiac is a tree resin and crude source of 2,5-di-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran (α-guaiaconic acid).[1] The phenolic α-guaiaconic acid acts as a colorimetric peroxidase substrate.[2][3][4] When reacted with an organic or inorganic oxidizing agent, the α-guaiaconic acid is oxidized to a blue-colored quinone. The guaiac reaction has been used to detect trace amounts of heme from hemoglobin in the presence of peroxide.
The Nobles test can be performed using 67% (w/v) gum guaiac diluted in 96% ethanol to analyze the level of extracellular oxidase production [5]

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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The Properties and Classification of the Oxidizing Enzymes, and Analogies between Enzymic Activity and the Effects of Immune Bodies and Complements.
E Whitley
The Biochemical journal, 4(3-4), 136-167 (1909-01-01)
Hermann Brenner et al.
European journal of cancer (Oxford, England : 1990), 49(14), 3049-3054 (2013-05-28)
There is increasing evidence that faecal immunochemical tests (FITs) for haemoglobin offer a number of advantages over traditional guaiac based faecal occult blood tests (gFOBTs). However, evidence on diagnostic performance from direct comparisons with colonoscopy findings in all participants in
Hermann Brenner et al.
International journal of cancer, 134(12), 2927-2934 (2014-01-01)
Guaiac-based fecal occult blood tests (gFOBTs) are the most commonly applied tests for colorectal cancer screening globally but have relatively poor sensitivity to detect colorectal neoplasms. Men have higher prevalences of colorectal neoplasms than women. In case of a positive
Nigel C Veitch
Phytochemistry, 65(3), 249-259 (2004-01-31)
Horseradish peroxidase is an important heme-containing enzyme that has been studied for more than a century. In recent years new information has become available on the three-dimensional structure of the enzyme and its catalytic intermediates, mechanisms of catalysis and the
Differential extracellular enzyme production in colonies of Coriolus versicolor, Phlebia radiata and Phlebia rufa: effect of gaseous regime.
White, N.
Journal of General Microbiology, 138, 2589-2598 (1992)

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