P9178

Prochlorperazin -dimaleat (Salz)

• Empirische Formel (Hill-System): C₂₀H₂₄ClN₃S · 2C₄H₄O₄
• CAS-Nummer: 84-02-6
• Molekulargewicht: 606.09
• NACRES: NA.77
• PubChem Substance ID: 57654570
• UNSPSC Code: 41116107
• EC Number: 201-511-3
• MDL number: MFCD00069330
• Form: powder

Eigenschaften

• form: powder
• Quality Segment: 200
• solubility: H₂O: slightly soluble 0.3 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL, methanol: soluble
• originator: GlaxoSmithKline
• SMILES string: OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1
• InChI: 1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
• InChI key: DSKIOWHQLUWFLG-SPIKMXEPSA-N
• Gene Information: human ... DRD2(1813)

Beschreibung

Biochem/physiol Actions

Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.

Phenothiazine antipsychotic; D₂ dopamine receptor antagonist; antispasmodic

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H336,H361d,H362
• pcodes: P202 - P260 - P263 - P264 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3
• target_organs: Central nervous system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves