D3658

1,9-Dideoxyforskolin from Coleus forskohlii

≥97%, solid

• Synonym(e): 7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one
• Empirische Formel (Hill-System): C₂₂H₃₄O₅
• CAS-Nummer: 64657-18-7
• Molekulargewicht: 378.50
• MDL-Nummer: MFCD00082318
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24893774
• NACRES: NA.77

Eigenschaften

• Assay: ≥97%
• Form: solid
• Optische Aktivität: [α]26/D +93.6°, c = 6.12 in chloroform(lit.)
• Farbe: white to off-white
• Löslichkeit: methanol: 28 mg/mL(lit.); DMSO: 3 mg/mL(lit.); chloroform: 50 mg/mL; ethanol: 6.6 mg/mL(lit.); dilute aqueous acid and base: insoluble(lit.)
• Lagertemp.: −20°C
• SMILES String: [H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)C3[C@@]1(C)CCCC2(C)C)C=C
• InChI: 1S/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16?,17-,18-,20-,21+,22-/m0/s1
• InChIKey: ZKZMDXUDDJYAIB-OJPJTMFRSA-N

Beschreibung

Anwendung

Useful as a negative control for forskolin.

Biochem./physiol. Wirkung

Biologically inactive forskolin analog. Does not stimulate adenylyl cyclase.

Leistungsmerkmale und Vorteile

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)