C5108
Cathepsin G from human sputum
≥0.2 units/mg protein, salt-free, lyophilized powder
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CAS-Nummer:
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
Technischer Dienst
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Unterstützung erhaltenbiological source
human sputum
form
salt-free, lyophilized powder
specific activity
≥0.2 units/mg protein
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... CTSG(1511)
Biochem/physiol Actions
Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.
Lagerklasse
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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E D Son et al.
Dermatology (Basel, Switzerland), 224(4), 352-360 (2012-07-05)
Cathepsin G, a serine protease that is activated by ultraviolet (UV) radiation, increases matrix metalloproteinase-1 (MMP-1) expression in fibroblasts through fibronectin (Fn) fragmentation and promotes the conversion of proMMP-1 to active MMP-1. This study investigated whether [2-[3-[[(1-benzoyl-4-piperidinyl)methylamino]carbonyl]-2-naphthalenyl]-1-(1-naphthalenyl)-2-oxoethyl]-phosphonic acid (KPA), a
Prasad Tongaonkar et al.
PloS one, 7(3), e32469-e32469 (2012-03-27)
The azurophilic granules of human neutrophils contain four α-defensins called human neutrophil peptides (HNPs 1-4). HNPs are tridisulfide-linked antimicrobial peptides involved in the intracellular killing of organisms phagocytosed by neutrophils. The peptides are produced as inactive precursors (proHNPs) which are
Hsiang-Ruei Liao et al.
Biochemical pharmacology, 84(2), 182-191 (2012-04-10)
Respiratory burst mediates crucial bactericidal mechanism in neutrophils. However, undesirable respiratory burst leads to pathological inflammation and tissue damage. This study investigates the effect and the underlying mechanism of 5-hydroxy-7-methoxyflavone (MCL-1), a lignan extracted from the leaves of Muntingia calabura