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556416

Sigma-Aldrich

Neues Methylenblau N

Dye content ~70 %

Synonym(e):

Basic Blue 24, Methylenblau N

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About This Item

Empirische Formel (Hill-System):
C18H22ClN3S
CAS-Nummer:
1934-16-3
Molekulargewicht:
347.91
Farbindexnummer:
52030
EG-Nummer:
217-696-9
MDL-Nummer:
MFCD00135878
UNSPSC-Code:
12171500
PubChem Substanz-ID:
24879556
NACRES:
NA.47

Form

powder, crystals or chunks

Zusammensetzung

Dye content, ~70%

mp (Schmelzpunkt)

190 °C (dec.) (lit.)

λmax

590 nm
632 nm (2nd)

εmax

≥29000 at 626-634 nm in water
≥30500 at 586-594 nm in water

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

[Cl-].CCNc1cc2[s+]c3cc(NCC)c(C)cc3nc2cc1C

InChI

1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1

InChIKey

NZYCYASKVWSANA-UHFFFAOYSA-M

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Verwandte Kategorien

Anwendung

New methylene blue N has been used as a photosensitizer for the photodynamic inactivation of Candida albicans.

Biochem./physiol. Wirkung

New methylene blue N can bind, neutralize and crosslink with RNA. This causes co-precipitation of ribosomal and residual RNA with the mitochondria and ferritin masses. These events make the living young erythrocytes as microscopically visible, dark-blue clusters and filaments, referred to as reticulum. New Methylene Blue N helps in counting of reticulocytes (erythrocytes containing RNA).

Leistungsmerkmale und Vorteile

In Lösungsmitteln löslicher kationischer Thiazinfarbstoff

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
0000164445
SHBN9708
SHBL0614
MKAA3423V
MKAA3423

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Fernando A Castro et al.
Veterinary surgery : VS, 34(6), 539-542 (2005-12-14)
To evaluate the accuracy of a new technique for perineural injection of the lateral palmar nerve and to determine frequency of inadvertent injection into the carpal synovial sheath with this technique. Prospective experimental study. Thirty equine cadaver forelimbs. Each of
M Wainwright et al.
Journal of chemotherapy (Florence, Italy), 13(5), 503-509 (2002-01-05)
The antibacterial activities of Methylene Blue and several of its congeners were measured against Yersinia enterocolitica, a gram-negative pathogen known to exhibit significant growth at 4 degrees C and thus constituting a threat to red blood cell concentrates which are
Puja Paul et al.
Journal of photochemistry and photobiology. B, Biology, 204, 111804-111804 (2020-02-03)
The ubiquitous influence of double stranded RNAs in biological events makes them imperative to gather data based on specific binding procedure of small molecules to various RNA conformations. Particular interest may be attributed to situations wherein small molecules target RNAs
M J Lopez et al.
American journal of veterinary research, 58(7), 786-790 (1997-07-01)
To determine the relation between epidural injectate volume (ml/kg of body weight) and its craniad migration in calves and pigs. 23 neonatal calves and 26 feeder pigs. Animals were randomly assigned to receive different volumes of new methylene blue (NMB
Won-gyun Son et al.
Veterinary anaesthesia and analgesia, 38(5), 510-515 (2011-08-13)
To examine the spread of solution in the epidural space of sternally recumbent dogs. Prospective experimental trial. Animals  Ten healthy adult Beagle dogs weighing 7.6 ± 1.1 kg. Dogs were anaesthetized with total intravenous propofol infusion, and placed in sternal recumbency. A volume
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