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35032

Supelco

Fenbendazol

VETRANAL®, analytical standard

Synonym(e):

5-(Phenylthio)-2-benzimidazolcarbaminsäure-methylester

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About This Item

Empirische Formel (Hill-System):
C15H13N3O2S
CAS-Nummer:
43210-67-9
Molekulargewicht:
299.35
Beilstein:
759077
EG-Nummer:
256-145-7
MDL-Nummer:
MFCD00144301
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329755115
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

clinical testing

Format

neat

SMILES String

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChIKey

HDDSHPAODJUKPD-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Chemical structure: benzimidazole
Fenbendazole is a thio substituted benzimidazole, which belongs to the group of anthelmintics. It can be widely used in veterinary medicine particularly, in the treatment of helminth infections.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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32567

Fenbendazol-d3, VETRANAL®, analytical standard

Piktogramme

Health hazardEnvironment
GHS08,GHS09

Signalwort

Warning

Gefahreneinstufungen

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

Zielorgane

Liver,lymph node,Stomach,Nervous system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCK6626
BCBZ7464
BCBS1202V
SZBF223XV
SZBB325XV

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Interaction between fenbendazole and piperonyl butoxide: pharmacokinetic and pharmacodynamic implications
Benchaoui.A.H and Mckellar.A.Q
The Journal of Pharmacy and Pharmacology, 48, 753-759 (1996)
Determination of fenbendazole and oxfendazole in liver and muscle using liquid chromatography?mass spectrometry
Blanchflower J.W, et al.
Analyst, 119, 1325-1328 (1994)
Niels C Kyvsgaard et al.
Veterinary parasitology, 181(2-4), 248-254 (2011-05-17)
Horses, mules and donkeys are indispensable farming and working animals in many developing countries, and their health status is important to the farmers. Strongyle parasites are ubiquitous in grazing horses world-wide and are known to constitute a threat to equine
Nilambra Dogra et al.
The Journal of biological chemistry, 287(36), 30625-30640 (2012-06-30)
In recent years, there has been a great deal of interest in proteasome inhibitors as a novel class of anticancer drugs. We report that fenbendazole (FZ) (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate) exhibits a potent growth-inhibitory activity against cancer cell lines but not normal
C Chassaing et al.
Journal of medicinal chemistry, 51(5), 1111-1114 (2008-02-15)
Highly water-soluble prodrugs 1a- g of anthelmintic benzimidazole carbamates 2a- g were synthesized. These prodrugs combine high aqueous solubility and stability with high lability in the presence of alkaline phosphatases. The veterinary utility of 1a was shown by a pharmacodynamic
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