A4673

Albendazol

analytical standard, ≥98%

• Synonym(e): Methyl-5-(propylthio)-2-benzimidazolcarbamat
• Empirische Formel (Hill-System): C₁₂H₁₅N₃O₂S
• CAS-Nummer: 54965-21-8
• Molekulargewicht: 265.33
• NACRES: NA.24
• PubChem Substance ID: 329770859
• UNSPSC Code: 41116107
• EC Number: 259-414-7
• MDL number: MFCD00083232

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• assay: ≥98%
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
• InChI: 1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
• InChI key: HXHWSAZORRCQMX-UHFFFAOYSA-N

Beschreibung

General description

Chemical structure: benzimidazole

Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.

Biochem/physiol Actions

Bindet an Tubulin und hemmt die Assemblierung der Mikrotubuli.

Sicherheitshinweise

• pictograms: GHS08,GHS09
• signalword: Warning
• hcodes: H361d,H373,H410
• pcodes: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral
• target_organs: Adrenal gland,Blood,male reproductive organs,spleen
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)