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01514

Supelco

[8]-Gingerol

analytical standard

Synonym(e):

(S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanon, 8-Gingerol

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About This Item

Empirische Formel (Hill-System):
C19H30O4
CAS-Nummer:
23513-08-8
Molekulargewicht:
322.44
Beilstein:
2059802
MDL-Nummer:
MFCD00877794
UNSPSC-Code:
85151701
PubChem Substanz-ID:
329747317
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Assay

≥95.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

food and beverages

Format

neat

Lagertemp.

2-8°C

SMILES String

CCCCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1

InChI

1S/C19H30O4/c1-3-4-5-6-7-8-16(20)14-17(21)11-9-15-10-12-18(22)19(13-15)23-2/h10,12-13,16,20,22H,3-9,11,14H2,1-2H3/t16-/m0/s1

InChIKey

BCIWKKMTBRYQJU-INIZCTEOSA-N

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Allgemeine Beschreibung

Gingerol is the pungent component of ginger roots. 8-Gingerol has a chain length of n8. It is a homologous series of phenolic ketones.
[8]-Gingerol is a bioactive constituent of ginger. It exhibits anti-inflammatory, anticancer, anti-oxidant and anti-ulcer properties.

Anwendung

It may be used as reference standard during quantification of 6-, 8- and 10-gingerols and 6-shogaol in human plasma using HPLC with electrochemical detection.
[8]-Gingerol may be used as a reference standard in the determination of [8]-gingerol in dietary supplements, food products and beverages using high-performance liquid chromatography (HPLC).

Biochem./physiol. Wirkung

[8]-Gingerol ist eine in Ingwer (Zingiber officinale) gefundene biologisch aktive Verbindung mit entzündungshemmender und antioxidativer Aktivität.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

This compound is commonly found in plants of the genus: zingiber

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCL4688
BCCH5924
BCCJ1388
BCCG7405
BCCC4919

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Shogaol ≥90% (HPLC)

Sigma-Aldrich

SMB00311

Shogaol

8-Shogaol phyproof® Reference Substance

PHL83910

8-Shogaol

10-Shogaol phyproof® Reference Substance

PHL83911

10-Shogaol

[6]-Gingerol, Zingiber officinale An antitumor, apoptosis-inducing compound of the ginger family that blocks EGF-induced cell transformation by inhibiting the activation of Activator Protein-1 (AP-1).

Sigma-Aldrich

345868

[6]-Gingerol, Zingiber officinale

Zingeron analytical standard

Supelco

88787

Zingeron

6-Gingerol phyproof® Reference Substance

PHL89201

6-Gingerol

Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin)

Sigma-Aldrich

C7727

Curcumin

High-performance liquid chromatography-electrospray mass spectrometric analysis of pungent constituents of ginger.
He, Xian-guo, et al.
Journal of Chromatography A, 796.2, 327-334 (1998)
Suzanna M Zick et al.
International journal of biomedical science : IJBS, 6(3), 233-240 (2010-11-13)
Zingiber officinale is one of the most commonly used spices. We developed a method to determine the main pungent ginger constituents, 6-, 8- and 10-gingerols and 6-shogaol in human plasma. Quantitation was achieved using a reversed-phase C(18) column using high-performance
High-performance liquid chromatographic analysis of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in ginger-containing dietary supplements, spices, teas, and beverages.
Schwertner HA and Rios DC
Journal of Chromatography. B, Biomedical Sciences and Applications, 856(1-2), 41-47 (2007)
Comparative antioxidant and anti-inflammatory effects of [6]-gingerol,[8]-gingerol,[10]-gingerol and [6]-shogaol.
Dugasani S, et al.
Journal of Ethnopharmacology, 127(2), 515-520 (2010)
Suzanna M Zick et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17(8), 1930-1936 (2008-08-19)
Ginger shows promising anticancer properties. No research has examined the pharmacokinetics of the ginger constituents 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in humans. We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of these
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