721778

N,N-Dimethylformamid-Dimethylsulfat-Addukt

95%

• Synonym(e): DMF-Dimethylsulfat, Methoxymethylen-N,N-dimethyliminium-methylsulfat
• Empirische Formel (Hill-System): C₅H₁₃NO₅S
• CAS-Nummer: 89712-45-8
• Molekulargewicht: 199.23
• MDL-Nummer: MFCD16621484
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 329763872
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Form: liquid
• Brechungsindex: n20/D 1.459
• Dichte: 1.349 g/mL at 25 °C
• SMILES String: CN(C)C=O.COS(=O)(=O)OC
• InChI: 1S/C3H7NO.C2H6O4S/c1-4(2)3-5;1-5-7(3,4)6-2/h3H,1-2H3;1-2H3
• InChIKey: UJKUJXVZLUTEAZ-UHFFFAOYSA-N

Beschreibung

Anwendung

DMF-Dimethyl sulfate adduct can be used as a reagent to synthesize:

• 2-azetidinones by a reaction between Schiff bases and substituted acetic acids.[1]
• Dimethylamino methylene derivatives, which can be employed in the preparation of fluoroquinolines and 3-amino-4-cyano pyrazole.[2]
• Cis β-sultams by [2 + 2] annulation of aldimines with sulfonic acids.[3]

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS05
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331,H315,H318,H334,H335,H350
• P-Sätze: P202 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): 190.0 °F - closed cup
• Flammpunkt (°C): 87.8 °C - closed cup