681334

2-(Trimethylsilyl)ethansulfonylchlorid

• Synonym(e): 2-Trimethylsilylethylsulfonylchlorid, SES-Cl
• Lineare Formel: (CH₃)₃SiCH₂CH₂SO₂Cl
• CAS-Nummer: 106018-85-3
• Molekulargewicht: 200.76
• MDL-Nummer: MFCD09265153
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24885632
• NACRES: NA.22

Eigenschaften

• Brechungsindex: n20/D 1.4444
• bp: 146.8 °C/760 mmHg
• Dichte: 1.059 g/mL at 25 °C
• Lagertemp.: 2-8°C
• SMILES String: C[Si](C)(C)CCS(Cl)(=O)=O
• InChI: 1S/C5H13ClO2SSi/c1-10(2,3)5-4-9(6,7)8/h4-5H2,1-3H3
• InChIKey: BLPMCIWDCRGIJV-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant involved in:

• Nucleophilic substitution for synthesis of nicotinamine and its analogs
• Regioselective metal-free oxidative cyclization of sulfonamides
• Annulation reactions
• Tin-free radical carbonylation of alkylsulfonyl derivatives
• Asymmetric aziridination

Reagent used for protection of an amino group as a SES-amide. The SES group can be conveniently removed by fluoride ion.

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H315,H319,H335
• P-Sätze: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 70.0 °F - closed cup
• Flammpunkt (°C): 21.1 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter