345717

1-Brom-2,3-difluor-benzol

98%

• Lineare Formel: BrC₆H₃F₂
• CAS-Nummer: 38573-88-5
• Molekulargewicht: 192.99
• MDL-Nummer: MFCD00061136
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24861344

Eigenschaften

• Assay: 98%
• Form: liquid
• Brechungsindex: n20/D 1.509 (lit.)
• Dichte: 1.724 g/mL at 25 °C (lit.)
• SMILES String: Fc1cccc(Br)c1F
• InChI: 1S/C6H3BrF2/c7-4-2-1-3-5(8)6(4)9/h1-3H
• InChIKey: RKWWASUTWAFKHA-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Microbial oxidation of 1-bromo-2,3-difluorobenzene by Pseudomonas putida strain 39/D and Escherichia coli recombinant microorganism (strain JM 109(pDTG601)) has been reported.[1]

Anwendung

1-Bromo-2,3-difluorobenzene may be used in the synthesis of potent, orally active Calcitonin gene-related peptide (CGRP) receptor antagonist (BMS-846372).[2] It may be used in the preparation of 2,3-difluorophenyl(dimethyl)phosphane.[3]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 141.8 °F - closed cup
• Flammpunkt (°C): 61 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter