284270

Phosphonessigsäure

98%

• Synonym(e): (Carboxymethyl)phosphonic acid, 2-Phosphonoacetic acid, Fosfonoacetic acid, Phosphonacetic acid
• Lineare Formel: (HO)₂P(O)CH₂CO₂H
• CAS-Nummer: 4408-78-0
• Molekulargewicht: 140.03
• EG-Nummer: 224-558-1
• MDL-Nummer: MFCD00004311
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24857145
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Form: powder or crystals
• mp (Schmelzpunkt): 143-146 °C (lit.)
• Löslichkeit: water: soluble 100 mg/mL, clear to very slightly hazy, colorless
• Funktionelle Gruppe: carboxylic acid
• SMILES String: OC(=O)CP(O)(O)=O
• InChI: 1S/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7)
• InChIKey: XUYJLQHKOGNDPB-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts[1]. It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase in vitro[2].

Anwendung

Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells[3]. It was also used as a phosphorus source for microbial growth in phosphate-independent manner[4].

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves