232130

[Bis-(trifluoracetoxy)-iod]-benzol

97%

• Synonym(e): BTI, Iodbenzol-I,I-bis-(trifluoracetat), PIFA
• Lineare Formel: (CF₃CO₂)₂IC₆H₅
• CAS-Nummer: 2712-78-9
• Molekulargewicht: 430.04
• Beilstein: 764767
• EG-Nummer: 220-308-0
• MDL-Nummer: MFCD00009672
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24853882
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: solid
• Eignung der Reaktion: reagent type: oxidant
• mp (Schmelzpunkt): 121-125 °C (lit.)
• SMILES String: FC(F)(F)C(=O)O[I](OC(=O)C(F)(F)F)c1ccccc1
• InChI: 1S/C10H5F6IO4/c11-9(12,13)7(18)20-17(6-4-2-1-3-5-6)21-8(19)10(14,15)16/h1-5H
• InChIKey: PEZNEXFPRSOYPL-UHFFFAOYSA-N

Beschreibung

Anwendung

Used for the direct α-hydroxylation of ketones under acidic conditions. Also employed as a p-fluorination reagent of 4-alkylphenols in the presence of HF·pyridine (cat. no. 184225) for synthesis of 4-fluorocyclohexa-2,5-dienones.
Reagent for the oxidation of N-acylhydrazones to 1,3,4-oxadiazoles. Promotes the cyclization of styryl amines to N-alkyl or N-aryl indoles.

Reactant or reagent for:

• Pummerer-like reactions
• Chemoselective deprotection of dimethoxybenzyl ethers
• Mediating oxidative cycloisomerization
• Tosyloxylation of anilides

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves