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Merck

GRIK2

glutamate receptor, ionotropic, kainate 2

Synonyme:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
L-Glutaminsäure -hydrochlorid, ,
Spezies
human
(±)-AMPA, solid,
Spezies
rat
(S)-AMPA, ≥97%,
Spezies
mouse, human, rat
Kainic acid monohydrate, ≥99% (TLC),
Spezies
human, mouse, rat
(Aminomethyl)phosphonsäure, 99%,
Spezies
rat, human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
CNQX, ≥98% (HPLC), solid,
Spezies
rat
NBQX Dinatriumsalz Hydrat, ≥98% (HPLC),
Spezies
human
DNQX, ≥98% (TLC),
Spezies
mouse, rat, human
(±)-AMPA, solid,
Spezies
rat
(S)-AMPA, ≥97%,
Spezies
mouse, human, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GluR6/7-Antikörper, Klon NL9, Kaninchen, monoklonal, culture supernatant, clone NL904, Upstate®,
Speziesreaktivität
human, mouse, rat
Anwendung
immunoprecipitation (IP)
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
western blot
Anti-GRIK2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
(±)-AMPA, solid,
Spezies
rat
Kainic acid monohydrate, ≥99% (TLC),
Spezies
human, mouse, rat
L-Glutaminsäure, ReagentPlus®, ≥99% (HPLC),
Spezies
rat, human
L-Glutaminsäure, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Spezies
rat, human
L-Glutaminsäure, BioUltra, ≥99.5% (NT),
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GRIK2 (1),
Spezies
human
MISSION® esiRNA, targeting human GRIK2 (2),
Spezies
human