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ADRA2A

adrenoceptor alpha 2A

Synonyme:
ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(150) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11551) adrenergic receptor, alpha 2a
  • Rat(25083) adrenoceptor alpha 2A
  • domestic guinea pig(100135475) adrenergic receptor, alpha 2a
  • chicken(428980) adrenergic, alpha-2A-, receptor
  • sheep(100170317) adrenoceptor alpha 2A
  • Domestic Rabbit(100009424) adrenoceptor alpha 2A
  • Zebrafish(266750) adrenergic, alpha-2A-, receptor
  • dog(486888) adrenoceptor alpha 2A
  • domestic cat(664736) adrenoceptor alpha 2A
  • sheep(101117291) adrenoceptor alpha 2A
  • naked mole-rat(101723298) adrenoceptor alpha 2A
  • cow(282135) adrenergic, alpha-2A-, receptor

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Clonidin -hydrochlorid, solid,
Spezies
human
Xylazin -hydrochlorid, ≥99.0% (HPLC),
Spezies
human
Guanfacin -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Guanfacin -hydrochlorid, ≥98% (HPLC),
Spezies
human
Guanabenz -acetat (Salz), powder,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
1-Naphthylmethylamin, 97%,
Spezies
rat
Yohimbin -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
1,2,3,4-Tetrahydroisoquinolin, 95%,
Spezies
rat, human
Idazoxan hydrochloride, ,
Spezies
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Adrenergic Receptor α-2A antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRA2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
canine, human, mouse, rat
Anwendung
ELISA
immunocytochemistry

immunofluorescence
Anti-ADRA2A antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
Anti-α2A Adrenergic Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, pig, rat
Anwendung
immunohistochemistry
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Mianserin -hydrochlorid, ,
Spezies
human
Agmatin -sulfat (Salz), ≥97%, powder,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
UK 14,304, ,
Spezies
human
BP897, >98% (HPLC), solid,
Spezies
human, rat
(−)-Norepinephrin, ≥98%, crystalline,
Spezies
human, rat
Haloperidol, powder,
Spezies
human, rat
Clozapin, ,
Spezies
human, rat

Proteins

Produktnummer
Beschreibung
Spezies
ChemiSCREEN Human α2A Adrenergic Receptor Membrane Preparation, Human alpha2A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Spezies
human