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Merck
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重要文件

SMB00580

Sigma-Aldrich

维生素 K 4

≥98% (HPLC)

同義詞:

2-Methyl-1,4-naphthalenediol diacetate, Menadiol diacetate, Vitamin K diacetate, acetomenaphthone

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About This Item

經驗公式(希爾表示法):
C15H14O4
CAS號碼:
分子量::
258.27
EC號碼:
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.79
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品質等級

化驗

≥98% (HPLC)

形狀

powder

技術

HPLC: suitable

顏色

white to off-white

儲存溫度

2-8°C

SMILES 字串

CC(OC1=CC(C)=C(OC(C)=O)C2=CC=CC=C21)=O

InChI

1S/C15H14O4/c1-9-8-14(18-10(2)16)12-6-4-5-7-13(12)15(9)19-11(3)17/h4-8H,1-3H3

InChI 密鑰

RYWSYCQQUDFMAU-UHFFFAOYSA-N

一般說明

Vitamin K4 (VK4), also referred to as 2-methyl-1,4-naphthalenediyldiacetate, is a synthetic hydrophilic form of vitamin K that belongs to menadione family. It is a diacetate form of VK3.[1]

生化/生理作用

Vitamin K4 elicits anti-cancer functionality and induces apoptosis in prostate carcinoma.[2]

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Slide 1 of 3

1 of 3

Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway.
Jiang Y
Pharmazie, 68, 442-448 (2013)
One-Pot Hydroacetylation of Menadione (Vitamin K3) to Menadiol Diacetate (Vitamin K4) by Heterogeneous Catalysis.
Dobrinescu C
Advanced Synthesis & Catalysis, 354, 1301-1306 (2012)
Yu Jiang et al.
Die Pharmazie, 68(6), 442-448 (2013-07-24)
Vitamin K4 (VK4) is a synthetic hydrophilic menadione compound, which is clinically used as hemostasis medicine. It has been reported that several vitamin Ks had inhibitory effects on various cancer cells. However, there is no report about VK4s anticancer activity.

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