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重要文件

47774

Supelco

维生素 (K2)

analytical standard

同義詞:

维生素 K2, 四烯甲萘醌, 甲萘醌 4

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About This Item

經驗公式(希爾表示法):
C31H40O2
CAS號碼:
分子量::
444.65
MDL號碼:
分類程式碼代碼:
12164500
PubChem物質ID:
暫時無法取得訂價和供貨情況

等級

analytical standard

品質等級

CofA

current certificate can be downloaded

特點

standard type fat soluble vitamin

包裝

ampule of 100 mg

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

形式

neat

儲存溫度

-10 to -25°C

SMILES 字串

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(C)C(=O)c2ccccc2C1=O

InChI

1S/C31H40O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,12,14,16,18-20H,9-11,13,15,17,21H2,1-6H3/b23-14+,24-16+,25-20+

InChI 密鑰

DKHGMERMDICWDU-GHDNBGIDSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

甲基萘醌 (K2),一种维生素 K2 同系物,具有四个异戊二烯单元。[1]有报道它能增强骨形成 [2],对血液凝血因子的产生起至关重要的角色。[3]

應用

有关合适仪器技术的更多信息,请参考产品的分析证书。如需进一步支持,请联系技术服务。
甲基萘醌可用作引用液相色谱串联质谱法测定人血浆中甲基萘醌的参比标准品。[4]

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor κ activation.
Ozaki I, et al.
Clinical Cancer Research, 13(7), 2236-2245 (2007)
Effects of menatetrenone on bone loss induced by ovariectomy in rats.
Akiyama Y, et al.
Japanese Journal of Pharmacology, 62(2), 145-153 (1993)
Simple and sensitive determination of menatetrenone and its epoxide metabolite in human plasma.
Kang W, et al.
Journal of Pharmaceutical and Biomedical Analysis, 44(5), 1178-1182 (2007)
Katheryne Z Edson et al.
Biochemistry, 52(46), 8276-8285 (2013-10-22)
Vitamin K plays an essential role in many biological processes including blood clotting, maintenance of bone health, and inhibition of arterial calcification. A menaquinone form of vitamin K, MK4, is increasingly recognized for its key roles in mitochondrial electron transport
Toshiro Sato et al.
Nutrition journal, 11, 93-93 (2012-11-13)
Vitamin K₂ contributes to bone and cardiovascular health. Therefore, two vitamin K₂ homologues, menaquinone-4 (MK-4) and menaquinone-7 (MK-7), have been used as nutrients by the food industry and as nutritional supplements to support bone and cardiovascular health. However, little is

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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